Korean J Dermatol.  2002 Apr;40(4):410-414.

Cutaneous T Cell Lymphoma, Pleomorphic, Small/medium-sized with Tissue and Blood Eosinophilia

• Oh SH
• Kim HS
• Kee JH
• Chang SN
• Kim D

Abstract

Cutaneous T cell lymphoma, pleomorphic, small/medium-sized is a primary cutaneous lymphoma that consists of less than 30% of large, pleomorphic T cells and mostly small/medium-sized, plemorphic T cells stained negatively CD30. This entity presents clinically with one or several red-purple nodules without patches & plaques and histopathologically infiltration of small/medium-sized T cells with a dense nodular or diffuse pattern in the dermis. Usually cellular infiltrations consist of atypical lymphocytes without eosinophils, plasma cells and neutrophils but there are cases infiltrated with atypical lymphocytes and eosinophils. We report a case of cutaneous T cell lymphoma, pleomorphic, small/medium-sized in a 55-year-old male who was presented with hard nodules on both elbows, both ankles, left 1st interdigital web, both wrists and both lateral sides of thigh. Histopathological findings showed diffuse and nodular infiltrates with atypical lymphocytes and eosinophils in the dermis, not involving the epidermis. Bone scan, bone marrow biopsy and CT scan taken to find out involvement of other organs showed normal finding except for eosinophilia at bone marrow biopsy.

Keyword

Cutaneous T cell lymphoma; Pleomorphic; Small/medium-sized; Eosinophil; EORTC classification

MeSH Terms

Ankle
Biopsy
Bone Marrow
Dermis
Elbow
Eosinophilia*
Eosinophils
Epidermis
Humans
Lymphocytes
Lymphoma
Lymphoma, T-Cell, Cutaneous*
Male
Middle Aged
Neutrophils
Plasma Cells
T-Lymphocytes
Thigh
Tomography, X-Ray Computed
Wrist