J Korean Rheum Assoc.  2001 Dec;8(4):282-286.

A Case of Adult Onset Still's Disease Associated with Epstein-Barr Virus

• Yu KJ
• Bae JS
• Seo YJ
• Lee JY
• Lim KJ
• Joh YL
• Yoon WC
• Kim CG
• Song YH
• Choe JY

Abstract

Adult onset Still 's disease (AOSD)is a rare,distinct clinical entity which affects predominantly young adults aged 16-35.It affects multiple organs,and at present,the etiology is still unclear.Because this disease has few diagnostic or confirmative test,the diagnosis is made by the differential diagnosis and by excluding other diseases.Several reports have suggested a viral trigger in the pathogenesis of this disease.It has some common clinical features ;abrupt onset, high fever,sore throat,transient maculopapular rash,lymphadenopathy,and hepatosplenomegaly.We describe a 17-year-old man who fulfilled the proposed diagnostic criteria of AOSD and had evidence of acute Epstein-Barr virus infection.He complained of intermittent high fever and myalgia for a week.He also had maculopapular rash,sore throat,multiple right cervical lymphadenopahty, and right ankle pain and swelling.After admission,intermittent fever persisted for a month,but diffuse myalgia and migrating arthralgia fluctuated.

Keyword

Adult onset Still 's disease; Epstein-Barr virus

MeSH Terms

Adolescent
Adult*
Ankle
Arthralgia
Diagnosis
Diagnosis, Differential
Fever
Herpesvirus 4, Human*
Humans
Myalgia
Still's Disease, Adult-Onset*
Young Adult