Korean J Gynecol Oncol.  2005 Sep;16(3):268-272.

Neoadjuvant chemotherapy in cervical carcinoma during pregnancy: Case report

• Mun SH
• Ryu HS
• Chang HJ
• Kim HY
• Chang KH
• Lee JP

Abstract

When the cervical cancer is diagnosed in early stage during pregnancy, the treatment can be postponed for fetal viability. This case presents a patient diagnosed as cervical cancer stage Ib1 during her pregnancy. The patient had 2 cycles of neoadjuvant chemotherapy (Paclitaxel-cisplatin) formerly and cesarean section was done at 33rd weeks of intrauterine pregnancy, then radical abdominal hysterectomy with bilateral pelvic lymph node dissection and paraaortic lymph node biopsy was immediately performed right after the delivery. For the baby born, there was neither complication nor congenital anomaly but mild bilateral ventriculomegaly seen on brain CT taken on 3 days after birth. This case offers a better chance for both mother and fetus while conserving fetal viability and managing the early cervical cancer during pregnancy through close follow up.

Keyword

Pregnancy; Cervix cancer; Neoadjuvant chemotherapy

MeSH Terms

Biopsy
Brain
Cesarean Section
Drug Therapy*
Female
Fetal Viability
Fetus
Follow-Up Studies
Humans
Hysterectomy
Lymph Node Excision
Lymph Nodes
Mothers
Parturition
Pregnancy*
Uterine Cervical Neoplasms