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Trends of axillary surgery in breast cancer patients with axillary lymph node metastasis: a comprehensive single-center retrospective study

Kim YJ, Kim HJ, Chung SY, Lee SK, Chae BJ, Yu J, Lee JE, Kim SW, Nam SJ, Ryu JM

Purpose: Based on the results of previous trials, de-escalation of axillary surgery after neoadjuvant chemotherapy (NAC) has increased in patients with axillary lymph node (ALN) metastasis at presentation. This study...
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Role of Doppler US and elastography prior to biopsy to identify candidates for avoidance of surgery following neoadjuvant chemotherapy for breast cancer

Kim SY, Lee HB, Han W, Lee SH, Chang JM, Cho N

Purpose: This study aimed to evaluate the role of Doppler ultrasound (US) and elastography to identify residual breast cancer for patients showing near complete response following chemotherapy on magnetic resonance...
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Neoadjuvant Chemotherapy in Asian Patients With Locally Advanced Gastric Cancer

Tong X, Zhi P, Lin S

Presently, surgery is the only treatment approach for gastric cancer and improving the prognosis of locally advanced gastric cancer is one of the key factors in promoting gastric cancer survival...
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Clinical Significance and Characteristics of Newly Detected Lesions on Breast MRI During Neoadjuvant Chemotherapy

Lee K, Nam KJ, Choo KS, Nam SB, Kim HY, Jung YJ, Kim JJ, Joo JH, Kim JY, Lee JW, Hwang JY, Park C

Purpose This study aimed to evaluate clinical significance and imaging findings of newly detected lesions on breast MRI while monitoring patients’ response to neoadjuvant chemotherapy (NAC). Materials and Methods We identified 291 patients...
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Extended Chemotherapy Followed by Staged Bilateral Nephron Sparing Surgery in Advanced Bilateral Wilms Tumor: Individualising Treatment Options for Optimal Outcome

Karagiri MR, Malik K, Radhakrishnan V, Raja A

Approximately 5% of Wilms tumors are bilateral. Multidisciplinary care including surgery, chemotherapy, and radiation has greatly improved the survival rates. With long-term survivorship, treatment should be planned to ensure quality...
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The Role of Neutrophil-to-Lymphocyte Ratio in Predicting Pathological Response for Resectable Non–Small Cell Lung Cancer Treated with Neoadjuvant Chemotherapy Combined with PD-1 Checkpoint Inhibitors

Sun X, Feng Y, Zhang B, Huang W, Zhao X, Zhang H, Yue D, Wang C

Purpose The aim of our study was to investigate the value of baseline and preoperative neutrophil-to-lymphocyte ratio (NLR) in predicting the pathological response and disease-free survival (DFS) of neoadjuvant chemotherapy alone...
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Systematic lymph node dissection during interval debulking surgery for advanced epithelial ovarian cancer: a systematic review and meta-analysis

Caruso G, Palaia I, Bogani G, Tomao F, Perniola G, Panici PB, Muzii L, Donato VD

Objective To evaluate the efficacy and safety of systematic lymph node dissection (SyLND) at the time of interval debulking surgery (IDS) for advanced epithelial ovarian cancer (AEOC). Methods Systematic literature review of studies...
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The Influence of Anxiety, Uncertainty, and Cancer Coping on the Quality of Life in Breast Cancer Patients Receiving Neoadjuvant Chemotherapy

Hyun DR, Kim YS

Objectives: The purpose of this study was to investigate the influence of anxiety, uncertainty, and cancer coping on the quality of life in breast cancer patients receiving neoadjuvant chemotherapy. Methods:...
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Neoadjuvant chemotherapy with gemcitabine and cisplatin followed by selective bladder preservation chemoradiotherapy in muscle-invasive urothelial carcinoma of bladder

Sung HH, Kim H, Kim R, Kim CK, Kwon GY, Park W, Song W, Jeong BC, Park SH

Purpose: To assess the safety and efficacy of gemcitabine and cisplatin as neoadjuvant chemotherapy followed by selective bladder preservation chemoradiotherapy in muscle-invasive bladder cancer (MIBC). Materials and Methods: Patients with clinical...
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Efficacy and safety of sequential neoadjuvant chemotherapy and short-course radiation therapy followed by delayed surgery in locally advanced rectal cancer: a single-arm phase II clinical trial with subgroup analysis between the older and young patients

Bananzadeh A, Hafezi AA, Nguyen N, Omidvari S, Mosalaei A, Ahmadloo N, Ansari M, Mohammadianpanah M

Purpose: This study was performed to investigate the efficacy and safety of short-course radiation therapy (SCRT) and sequential chemotherapy followed by delayed surgery in locally advancer rectal cancer with subgroup...
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Insights into ovarian cancer care: report from the ANZGOG Ovarian Cancer Webinar Series 2020

Obermair A, Beale P, Scott CL, Beshay V, Kichenadasse G, Simcock B, Nicklin J, Lee YC, Cohen P, Meniawy T

Epithelial ovarian cancer (EOC) is among the top ten causes of cancer deaths worldwide, and is one of the most lethal gynecological malignancies in high income countries, with incidence and...
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Fertility-sparing surgery for women with stage I cervical cancer of 4 cm or larger: a systematic review

Donato VD, Caruso G, Sassu CM, Santangelo G, Bogani G, Plotti F, Sorbi F, Perniola G, Palaia I, Terrin G, Angioli R, Panici PB, Muzii L

Objective To investigate current evidence on oncological, fertility and obstetric outcomes of patients with stage I cervical cancer of 4 cm or larger undergoing fertility-sparing surgery (FSS). Methods Systematic review of studies including...
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Complete response of locally advanced left-sided pancreatic cancer after modified FOLFIRINOX chemotherapy followed by conversion surgery: A case report

Kim SJ, Park JY, Hwang HS, Kang CM

For years, neoadjuvant chemotherapy for locally advanced pancreatic cancer is being investigated and radical surgical resection with laparoscopic approach is getting up to speed. Pathological complete remission is known as...
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Current approaches in intensification of long-course chemoradiotherapy in locally advanced rectal cancer: a review

Haddad P, Ghalehtaki R, Saeedian A, Farhan F, Babaei M, Aghili M

Rectal cancer is one of the most prevalent cancers in the world. In many countries, the current standard of care is long-course chemoradiation (CRT), followed by total mesorectal excision. Some...
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The Predictive Values of Pretreatment Controlling Nutritional Status (CONUT) Score in Estimating Shortand Long-term Outcomes for Patients with Gastric Cancer Treated with Neoadjuvant Chemotherapy and Curative Gastrectomy

Jin H, Zhu K, Wang W

Purpose: Previous studies have demonstrated the usefulness of the controlling nutritional status (CONUT) score in nutritional assessment and survival prediction of patients with various malignancies. However, its value in advanced...
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The Prognostic Value of Lymph Node Ratio after Neoadjuvant Chemotherapy in Patients with Locally Advanced Gastric Adenocarcinoma

Zhu K, Jin H, Li Z, Gao Y, Zhang Q, Liu X, Yu J

Purpose: This study aimed to investigate the prognostic value of lymph node ratio (LNR) in patients with locally advanced gastric cancer who received neoadjuvant chemotherapy. Materials and Methods: We retrospectively enrolled...
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A Preoperative Nomogram for Predicting Chemoresistance to Neoadjuvant Chemotherapy in Patients with Locally Advanced Cervical Squamous Carcinoma Treated with Radical Hysterectomy

Ou Z, Zhao D, Li B, Wang Y, Liu S, Zhang Y

Purpose This study aimed to investigate the factors associated with chemoresistance to neoadjuvant chemotherapy (NACT) followed by radical hysterectomy (RH) and construct a nomogram to predict the chemoresistance in patients...
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Evaluation and Comparison of Predictive Value of Tumor Regression Grades according to Mandard and Becker in Locally Advanced Gastric Adenocarcinoma

Tong Y, Zhu Y, Zhao Y, Shan Z, Liu D, Zhang J

Purpose Tumor regression grade (TRG) has been widely used in gastrointestinal carcinoma to assess pathological responses to neoadjuvant chemotherapy (NCT). There are various standards without a consensus, and it is still...
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Decrease of peripheral blood lymphocyte count predicts response to neoadjuvant chemotherapy in breast cancer patients

Lee OH, Min SY

Purpose: Pathologic complete response (pCR) after neoadjuvant chemotherapy (NAC) holds promise as a significant prognostic factor to predict NAC response in breast cancer patients. The absolute peripheral blood lymphocyte (PBL)...
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Node-Positive Bladder Cancer After Neoadjuvant Chemotherapy Followed by Radical Cystectomy: A Single-Center Retrospective Study

Cho JH, Kwon GY, Kang M, Sung HH, Jeon HG, Jeong BC, Seo SI, Jeon SS, Lee HM, Choi HY, Lee SJ, Park SH

Purpose: There remains a lot of unmet need to increase understanding of node-positive (ypN+) muscle invasive bladder cancer (MIBC) after neoadjuvant chemotherapy and radical cystectomy to decide the appropriate therapeutics. Materials...
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