Korean J Dermatol.
2000 Oct;38(10):1366-1369.
A Case of Generalized Eruptive Histiocytoma in Childhood
- Affiliations
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- 1Department of Dermatology, Yonsei University College of Medicine, Seoul, Korea.
Abstract
- Generalized eruptive histiocytoma is a papular, nonlipidic, self-healing histiocytosis affecting mainly adults. Clinically the disease is characterized by an asymptomatic, widespread, frequently symmetrical eruption of numerous dark red or bluish red papules. In adults the lesions are symmetrically distributed and may involve mucous membranes, while in children the lesions are irregularly scattered over the entire body and mucous membranes spare. We herein report a case of generalized eruptive histiocytoma developed in a 3-year-old boy. He was seen with brownish, flat papules on the face, trunk and both proximal portions of extremities. Histological and immunohistochemical investigation revealed monomorphous infiltration of S-100, CD1a negative, lysozyme positive histiocytes in the upper dermis. Neither cells with foamy cytoplasm nor giant cells was found. He did not show any disease progression without treatment, so now in regular follow-up for exaggeration.
