J Korean Pediatr Soc.
1998 Jul;41(7):989-993.
A Case of Pancreatitis associated with Systemic Lupus Erythematosus
- Affiliations
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- 1Department of Pediatrics, College of Medicine, Pusan National University, Pusan, Korea.
Abstract
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Systemic lupus erythematosus (SLE), an autoimmune disease with multisystemic involvement, has been reported to be associated with a number of gastrointestinal complications. But pancreatitis is an unusual complication of SLE, occuring in only 3-4% of lupus cohort. Multiple mechanisms contributing to pancreatitis associated with SLE have been demonstrated which include vasculitis, necrotizing pancreatitis, corticosteroid administration, and vascular thrombosis. We experienced a case of pancreatitis associated with SLE in a 14-year-old girl. The cause of pancreatitis may be related secondarily to vascular thrombosis, since there were several clinical and laboratory findings suggesting thromboembolic phenomena, including false-positive test for syphilis, prologation of PT/aPTT, and pulmonary embolism.