J Korean Soc Med Ultrasound.  1999 Sep;18(3):193-198.

Fibroadenomas: Sonographic-Pathologic Correlation

• Kim MS
• Choi HY
• Kim EA
• Lee SW
• Sung SH

Abstract

PURPOSE: To correlate sonographic appearance and histopathologic findings of fibroadenomas.
MATERIALS and METHODS
Forty-one biopsy-proven fibroadenomas were retrospectively evaluated for sonographic-pathologic correlation. The fibroadenomas were histologically classified into sclerotic, myxoid, glandular and mixed type. The stromal cellularity and fibrosis were also classified into mild and severe. The internal echotexture and posterior acoustic enhancement of mass in ultrasonogram were correlated with histopathologic findings .
RESULTS
The pathologic types of fibroadenomas were sclerotic in sixteen, myxoid in thirteen, and glandular or mixed in each of six cases. Most of the sclerotic type showed hypoechoic internal echotexture (68.8%) and myxoid and glandular types showed isoechoic internal echotexture (84.6%, 83.3% respectively). The hypoechoic masses showed 12 cases of mild (75.0%) and 4 cases of severe (25.0%) in cellularity and 3 cases of mild (18.7%) and 13 cases (81.3%) of severe degree in fibrosis. Most of the myxoid type (77%) showed posterior enhancement, and most of the sclerotic type (87.5%)did not show posterior enhancement on ultrasonogram. Posterior enhancement was absent in 22 cases, in which 4 cases (18.2%) showed mild and 18 cases (81.2%) showed severe degree of fibrosis.
CONCLUSION
Sclerotic type with mild cellularity and severe fibrosis on histopathology showed hypoechogenicity on ultrasonogram; whereas myxoid and glandular types were predominantly isoechoic. Most of the myxoid type showed posterior enhancement. Sclerotic type with mild cellularity and severe fibrosis did not show posterior enhancement.

MeSH Terms

Acoustics
Breast Neoplasms
Fibroadenoma*
Fibrosis
Retrospective Studies
Ultrasonography