Somatosensory, Brainstem Auditory and Visual Evoked Potentials in Patients with Functional Dyspepsia

Han, Seung Yeup; Lim, Jeong Geun; Kang, Young Woo

Abstract

BACKGROUND/AIMS: Although gastrointestinal dysmotility have played an important role in patho- physiology of functional dyspepsia, visceral perception abnormalities due to visceral hypersensi- tivity are now thought to be a major pathophysiologic mechanism of functional dyspepsia. Visceral hypersensitivity occurred at both visceral afferent pathway and autonomic regulation of central system. The present study was performed to evaluate the possible role of abnormal central percep- tion in the pathophysiology of functional dyspepsia by using various evoked potentials.
METHODS
The study population consisted of 22 patients with functional dyspepsia and 22 healthy volunteers attending Keimyung University hospital from June 1995 to December 1995. They were studied somaiosensory evoked potentials(SSEP), brainstem auditory evoked potentials(BAEP) and visual evoked potentials(VEP) and compared the absolute latencies, interpeak latencies and amplitudes of each evoked potential between two groups.
RESULTS
There were no significant differences in absolute latencies of EP, N13, N19 and P22 waves and amplitudes of EP, N13 and N19/P22 at SSEP between functional dyspepsia and norrnal control. There were no significant differences in absolute latencies of I, II, III, IV and V waves, and interpeak latencies of I -III, m- V and I V at BAEP between functional dyspepsia and normal control. There were no significant differences in absolute latencies and amplitudes of P100 at VEP between functional dyspepsia and normal control.
CONCLUSIONS
The present study could not reveal abnormal central percepition by using somatosensory, auditory and visual evoked potentials in patients with functional dyspepsia.