J Korean Neurol Assoc.  1997 Oct;15(5):1199-1202.

Guillain-Barre syndromes accompanied by optic neuritis

• Kim DH
• Yoon YC
• Lee KK
• Kwon OS

Abstract

Although Guillain Barre sydrome(GBS) is known to be a demylinating disease of the peripheral nervous system, it has been rarely repored that GBS was accompanied by demyelinating disease of the central nervous system such as multiple sclerosis, optic neuritis or acute disseminated encephalomyelitis. We experienced a patients with GBS who developed unilateral opticneuritis. A 19-year-old male patient was presented with ascending weakness. A few days later, he complained of decreased visual acuity and pain on the right eye. Cerebrospinal fluid findings were compatible with GBS and serial visual evoked potential studies were indicative of optic neuritis. This case suggests common pathogenesis between central and peripheral demyelinating diseases.

Keyword

Gillain-Barre syndrome; Optic neuritis; Demyelinating disease

MeSH Terms

Central Nervous System
Cerebrospinal Fluid
Demyelinating Diseases
Encephalomyelitis, Acute Disseminated
Evoked Potentials, Visual
Humans
Male
Multiple Sclerosis
Optic Neuritis*
Peripheral Nervous System
Visual Acuity
Young Adult