J Korean Endocr Soc.  2007 Apr;22(2):149-152. 10.3803/jkes.2007.22.2.149.

A Case of Graves' Disease with Ulcerative Colitis

• Jung PM
• Lee MY
• Koh JH
• Shin JY
• Shin YG
• Jo MY
• Chung CH

• KMID: 1523097
• DOI: http://doi.org/10.3803/jkes.2007.22.2.149

Keyword

Autoimmune thyroid disease; Graves' disease; Immune mechanism; Inflammatory bowel disease; Ulcerative colitis

MeSH Terms

Colitis, Ulcerative*
Graves Disease*
Inflammatory Bowel Diseases
Ulcer*

Figure

• 

  Fig. 1 Thyroid sonographic findings. Transverse sonogram of the right thyroid lobe shows thyroid gland enlargement with heterogeneous echogenicity. Transverse doppler sonogram of the right thyroid lobe shows markedly increased blood flow. The thickness of the isthmus of thyroid is showed as 0.8 cm.

• 

  Fig. 2 Colonoscopic findings. Diffuse inflammation and ulceration was observed at rectum from anus to upper part above 20 cm.

• 

  Fig. 3 Pathologic findings. A, dense lymphoplasmacytic inflammation involves the entire biopsy. Some crypts are branched (architectural distortion), indicating previous injury and regeneration. (H&E stain, ×40) B, neutrophils perforate the crypt epithelium (cryptitis). Diffuse lymphoplasmacytic inflammation, and a prominent germinal center is also present. (H&E stain, ×100)

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