J Korean Surg Soc.  2007 Aug;73(2):183-187.

Colonic Schwannoma

• Kang DB
• Kim SH
• Oh JT
• Park WC
• Lee JK
• Kim HS

Abstract

Schwannoma is a common soft tissue tumor, but it appears to be rare among the spindle cell mesencymal tumors of the gastrointestinal tract. Gastrointestinal Schwannomas (GIS) are rare and most of them originate in the stomach or the small bowel. GIS of the colon is extremely rare. The most important issue to be addressed for this type of tumor is the difficulty in making the correct preoperative diagnosis. Less than 10% of cases have been diagnosed as schwannoma preoperatively. A 58-year-old man was found to have a 3.5cm sized submucosal transverse colon tumor on the preoperative colonoscopy, abdominal CT and MRI. Wedge resection was done and the submucosal mass was diagnosed as schwannoma on the immunochemical staining. The immunochemical results were negative staining for CD 117(KIT) and CD 34 and positive staining for S-100 protein, which is all consistent with schwannoma. We report here on the first case of colonic schwannoma in Korea, along with a review of the literature.

Keyword

Gastrointestinal schwannoma; S-100 protein; Colon

MeSH Terms

Colon*
Colon, Transverse
Colonoscopy
Diagnosis
Gastrointestinal Tract
Humans
Korea
Magnetic Resonance Imaging
Middle Aged
Negative Staining
Neurilemmoma*
S100 Proteins
Stomach
Tomography, X-Ray Computed
S100 Proteins