Korean J Aerosp Environ Med.  2003 Sep;13(3):125-130.

The Effect on Age, Body Weight, Height, Body Mass Index and Smoking to Coagulation Factor VII, VIII and Fibrinogen in Pilots

• Jung HS
• Shin YD
• Back SH
• Jo JB
• Park NW
• Lee WK
• Lee J
• Lim HK
• Kim JH

Abstract

BACKGROUND
The pilots with cardiovascular events have a possibility for a risk of suffering from sudden incapacitation which is closely related to flying safety. The coagulation factors such as fibrinogen, factor VII, and factor VIII are possibly related to cardiovascular events. Several studies for general population have shown that an increase of those coagulation factors with age, a correlation of Factor VII and fibrinogen with BMI, and of fibrinogen with smoking. However, this study is to find out whether pilots' age, body weight, body mass index (BMI) and smoking are related to the baseline measurement of coagulation factor VII, factor VIII and fibrinogen. METHOD: Samples were taken from 21 pilots from Asiana Airlines: 11 smokers and 10 non-smokers. In order to measure the relationship between age, body weight, BMI, and the coagulation factors, Pearson correlation was used in this analysis. Independent two sampled t-test was used to analyze the correlation between smoking and the coagulation factors.
RESULTS
Mean age, mean height, mean body weight and mean BMI of pilots were examined: 38 years, 171.81 cm, 70.67 Kg and 23.94 Kg/m(2). Mean fibrinogen, mean factor VII, and mean factor VIII were also obtained: 236.0 mg/dl, 92.93%, and 60.16%. The coagulation factor VII, factor VIII and fibrinogen were not significant related to age, body weight, BMI, smoking of pilots.
CONCLUSION
This study has no correlation between age, body weight, BMI, smoking and the coagulation factors because the age of this study does not have pilots with over 60 years old and healthy behaviors (e.g., exercise, smoking, drinking, etc.) of most pilots are relatively well.

Keyword

Fibrinogen; Factor VII; Factor VIII; Cardiovascular disease

MeSH Terms

Blood Coagulation Factors*
Body Height*
Body Mass Index
Body Weight*
Cardiovascular Diseases
Diptera
Drinking
Factor VII*
Factor VIII
Fibrinogen*
Humans
Middle Aged
Smoke*
Smoking*
Blood Coagulation Factors
Factor VII
Factor VIII
Fibrinogen
Smoke