Korean J Biol Psychiatry.  2006 Feb;13(1):38-42.

A Case of Idiopathic Basal Ganglia Calcification with Dementia

Affiliations
  • 1Clinical Trial Center, Chonnam National University Hospital, Kwangju, Korea. isshin@chonnam.ac.kr
  • 2Department of Psychiatry, Chonnam National University Medical School, Gwangju, Korea.
  • 3Department of Psychiatry, Hwasun Chonnam National University Hospital, Hwasun, Korea.

Abstract

The case of a 66-year-old woman with coexisting idiopathic basal ganglia calcification(IBGC) and dementia was presented. The calcification was detected in bilateral basal ganglia, dentate nucleus, and thalamus by brain imaging. Serum calcium and phosphorus levels were normal. The underlying diseases of calcification of basal ganglia such as parathyroid dysfunction and other infectious, toxic, or metabolic illness were excluded. The patient had memory impairment and frontal executive dysfunction without aphasia, agnosia, apraxia, and visuospatial impairment in neuropsychological test. It suggested that the cognitive impairment might be due to the dysfunction of frontal-subcortical circuit.

Keyword

Basal ganglia; Calcification; Dementia; Neuropsychiatric symptom

MeSH Terms

Aged
Agnosia
Aphasia
Apraxias
Basal Ganglia*
Calcium
Cerebellar Nuclei
Dementia*
Female
Humans
Memory
Neuroimaging
Neuropsychological Tests
Phosphorus
Thalamus
Calcium
Phosphorus
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