Korean J Ophthalmol.  2012 Dec;26(6):407-413. 10.3341/kjo.2012.26.6.407.

A Comparative Study of the Effect of Fibrin Glue versus Sutures on Clinical Outcome in Patients Undergoing Pterygium Excision and Conjunctival Autografts

• Cha DM
• Kim KH
• Choi HJ
• Kim MK
• Wee WR

• KMID: 1499677
• DOI: http://doi.org/10.3341/kjo.2012.26.6.407

Abstract

PURPOSE
To compare the effect of using fibrin glue or 10-0 nylon sutures on the clinical outcome of patients undergoing pterygium excision and conjunctival autografting.
METHODS
We retrospectively reviewed the medical records of 52 eyes from 46 patients who underwent pterygium excision and conjunctival autografting and were followed up for more than 3 months. The operation duration, postoperative inflammation, complications, and recurrence rates were compared between groups of 20 patients (22 eyes) for whom fibrin glue was used (fibrin glue group) and 26 patients (30 eyes) for whom suturing was performed with 10-0 nylon (suture group) in pterygium excision and conjunctival autografting.
RESULTS
The operation duration was 27.71 (5.22) minutes in the fibrin glue group and 43.30 (8.18) minutes in the suture group (p = 0.000). Seven days after the operation, the fibrin glue group showed milder conjunctival inflammation than the suture group (p = 0.000). Postoperative complications and corneal recurrence rates were not statistically different between the two groups.
CONCLUSIONS
The use of fibrin glue in pterygium excision with conjunctival autografting is likely to be a more effective, safer procedure than suturing.

Keyword

Conjunctival autograft; Fibrin glue; Pterygium excision

MeSH Terms

Adult
Aged
Aged, 80 and over
Conjunctiva/*transplantation
Female
Fibrin Tissue Adhesive/*pharmacology
Follow-Up Studies
Humans
Male
Middle Aged
Patient Satisfaction
Pterygium/*surgery
Retrospective Studies
Suture Techniques/*instrumentation
*Sutures
Time Factors
Tissue Adhesives/pharmacology
Transplantation, Autologous
Fibrin Tissue Adhesive
Tissue Adhesives