Korean J Pediatr.
2008 Dec;51(12):1320-1323. 10.3345/kjp.2008.51.12.1320.
Epidemiologic study of Kawasaki disease in 6 months old and younger infants
- Affiliations
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- 1Department of Pediatrics, College of Medicine, Inje University, Seoul, Korea. yongpw@hanmail.net
- 2Department of Pediatrics, College of Medicine, Catholic University, Seoul, Korea.
- 3Department of Pediatrics, College of Medicine, University of Ulsan, Seoul, Korea.
- 4Department of Pediatrics, College of Medicine, Soonchunhyang University, Buchun, Korea.
- 5Department of Pediatrics, College of Medicine, Kyunghee University, Seoul, Korea.
- 6Department of Pediatrics, College of Medicine, Chonnam National University, Kwangju, Korea.
- 7Department of Pediatrics, College of Medicine, Keimyung University, Taegu, Korea.
- 8Department of Pediatrics, College of Medicine, Kyungpook National University, Taegu, Korea.
- 9Department of Pediatrics, College of Medicine, Sungkyunkwan University, Seoul, Korea.
- 10Department of Pediatrics, College of Medicine, Seoul National University, Seoul, Korea.
- KMID: 1494522
- DOI: http://doi.org/10.3345/kjp.2008.51.12.1320
Abstract
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PURPOSE: The aim of this study was to investigate the epidemiologic status of Kawasaki disease (KD) in infants < or =6 months of age.
METHODS
For the epidemiologic study of KD in Korea, data from 22,674 KD patients were collected from 1997 to 2005 on a 3 -year basis by a retrospective survey. From this survey, data of 1,739 KD patients < or =6 months of age were analyzed and compared with those of KD patients >6 months of age.
RESULTS
A total of 1,739 patients < or =6 months of age, including 1,088 males and 651 females, represented 7.7% of total KD patients. These subjects included 22 patients aged <1 month, 171 patients aged 1-2 months, 304 patients aged 2-3 months, 407 patients aged 3-4 months, 372 patients aged 4-5 months, and 463 patients aged 5-6 months. Their mean age of onset was 4.3 months, and the male-to-female ratio was 1.67 :1 . Incidences of coronary arterial (CA) abnormalities (21.0% versus 18.7%) and CA aneurysms (4.7% versus 3.1%) detected by echocardiography showed differences between patients with KD younger and older than 6 months, respectively.
CONCLUSION
Comparison of data from KD patients >6 months old with data from 1,739 KD patients < or =6 months old showed significantly higher incidences of CA abnormalities and CA aneurysms in the younger patients.
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