J Korean Soc Hypertens.  2011 Dec;17(4):156-165. 10.5646/jksh.2011.17.4.156.

Association of Hypertension and Obesity with Echocardiographic Left Ventricular Hypertrophy or Microalbuminuria in a General Population in South Korea

• Kim YM
• Han SW
• Kim BK
• Kim MK
• Choi BY
• Shin JH

• KMID: 1492133
• DOI: http://doi.org/10.5646/jksh.2011.17.4.156

Abstract

BACKGROUND
Both left ventricular hypertrophy (LVH) and microalbuminuria (MA) are well described markers or surrogate for cardiovascular outcome. Many factors are known to be related to the two markers which are encountered together in some patients. But the epidemiological backgrounds for the two markers are not clearly demonstrated so far.
METHODS
Measurements of echocardiographic left ventricular mass index (LVMI) and MA were introduced to the population survey in Yangpyeong County, Korea in 2005 and 2006 for 1,767 among 2,028 subjects. The criteria for MA were 17-250 mg/g of albumin creatinine ratio (ACR) in male and 25-355 mg/g in female. 1,636 data were analyzed.
RESULTS
Age was 60.9 +/- 10.4 years and the proportion of female was 59.4% (972). Body mass index (BMI) was 24.7 +/- 3.21 kg/m2 and blood pressure were 124.1 +/- 17.3 mm Hg/80.0 +/- 10.5 mm Hg. LVMI was 45.3 +/- 11.6 g/m2.7 and ACR was 23.9 +/- 150.9 mg/g. Prevalence of LVH and MA were 23.5% and 12.2%, respectively. In male/female, odds ratios for MA were 1.035 (range, 1.010-1.061)/1.01 (range, 0.988-1.032) for age, 0.962 (range, 0.882-1.049)/0.941 (range, 0.881-1.006) for BMI, 1.754 (range, 1.097-2.804)/2.158 (range, 1.413-3.298) for hypertension (HTN), 4.87 (range, 2.883-8.226)/2.154 (range, 1.311-3.539) for diabetes, 1.005 (range, 0.999-1.012)/1.007 (range, 1.002-1.012) for cholesterol, and 1.011 (range, 0.987-1.035)/1.011 (range, 0.994-1.029) for LVH.
CONCLUSIONS
In a population level, even if diabetes was strongest factor for MA, HTN is also independent factor for MA in both genders.

Keyword

Hypertrophy; Left ventricular; Albuminuria; Hypertension; Obesity

MeSH Terms

Albuminuria
Blood Pressure
Body Mass Index
Cholesterol
Creatinine
Female
Humans
Hypertension
Hypertrophy
Hypertrophy, Left Ventricular
Korea
Male
Obesity
Odds Ratio
Prevalence
Republic of Korea
Cholesterol
Creatinine

Reference

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