J Breast Cancer.  2008 Sep;11(3):151-155. 10.4048/jbc.2008.11.3.151.

Intracystic Papillary Carcinoma in the Male Breast: A Case Report

• Yun SS
• Choi SH
• Kim SK
• Park JK
• Baek JM
• Lee DH
• Seo YJ
• Park WC
• Song BJ
• Oh SJ
• Lee S
• Jung SS
• Seo EJ
• Min KO

• KMID: 1485109
• DOI: http://doi.org/10.4048/jbc.2008.11.3.151

Abstract

Intracystic papillary carcinoma of the breast is a variant of ductal carcinoma in situ (DCIS) characterized by the presence of papillary carcinoma within a cystically dilated duct. DCIS of the male breast is an uncommon disease, accounting for approximately 7% of all male breast carcinomas. Most DCIS in men is of the papillary type. We experienced one case of intracystic papillary carcinoma in the right breast of a 49-yr-old male and report the case with a review of the literature.

Keyword

Male breast tumor; Intracystic papillary carcinoma

MeSH Terms

Accounting
Breast
Breast Neoplasms, Male
Carcinoma, Intraductal, Noninfiltrating
Carcinoma, Papillary
Humans
Male
Multiple Endocrine Neoplasia Type 1

Figure

• 

  Fig 1 Ultrasonographic findings. This tumor is a 2.3×1.6 cm sized well marginated cystic mass with an internal fluid level (arrow) and an irregular solid component in the right subareolar area.

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  Fig 2 Fine needle aspiration cytology findings. There are two papillary structures consisting of a central core of stromal cells surrounded by layers of epithelial cells in a hemorrhagic background (H&E stain, ×100).

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  Fig 3 Gross specimen after excision. The tumor is a well-encapsulated round mass composed of friable solid tissue in a papillary pattern (arrow) and brown fluid.

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  Fig 4 Histopathologic findings (H&E stain A×100, B×200). Papillary proliferations of the tumor cells with a fibrovascular core within the cystically dilated duct are observed. The high power view shows the layering of tumor cells, loss of nuclear polarity, hyperchromasia and lack of myoepithelial cell layer.

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  Fig 5 Immunohistochemical stains of estrogen receptor is positive (A×200) and SMMHC is negative (B×200).

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