Korean J Dermatol.
2008 Sep;46(9):1257-1261.
A Case of Doxifluridine-Induced Multiple Atypical Moles on the Palm and Sole of a Patient Taking Immunosuppressive Agents
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- 1Department of Dermatology, University of Ulsan College of Medicine, Asan Medical Center, Seoul, Korea. 1052_hihi@hanmail.net
Abstract
- Doxifluridine is a pyrimidine derivative and is activated to 5-fluorouracil by pyrimidine phosphorylase. Multiple acral hyperpigmented macules have been reported in patients treated with systemic 5-fluorouracil or some of its prodrugs. However, there have been no reports of this adverse event being induced by doxifluridine. Herein we present a 42-year-old woman with multiple pigmented lesions on the palm and sole after chemotherapy with oral doxifluridine.
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