J Korean Radiol Soc.
2008 Jan;58(1):97-104. 10.3348/jkrs.2008.58.1.97.
Lesion Conspicuity of Hypoxic-ischemic Encephalopathy in Neonates: a Comparison of Various Magnetic Resonance Imaging Sequences
- Affiliations
-
- 1Department of Diagnostic Radiology, Pusan National University Hospital, Busan, South Korea. hakjink@pusan.ac.kr
- 2Department of Pediatrics, Pusan National University Hospital, Busan, South Korea.
- KMID: 1479155
- DOI: http://doi.org/10.3348/jkrs.2008.58.1.97
Abstract
-
PURPOSE: To determine which magnetic resonance (MR) imaging sequence demonstrates the highest lesion conspicuity for lesion detection in neonates with hypoxic-ischemic encephalopathy (HIE).
MATERIALS AND METHODS
In 30 neonates with HIE, lesion conspicuity in different brain structures was retrospectively compared on T1-weighted images, T2-weighted images, fluid-attenuated inversion recovery images, and diffusion-weighted images (DWI). The brain structures were categorized as follows: cerebral cortex; cerebral white matter; deep gray matter; posterior limb of the internal capsule (PLIC); brain stem; and cerebellum.
RESULTS
For the deep gray matter, T1-weighted imaging was superior to the other sequences in lesion detection of 9 of 14 patients (64.3%), whereas DWI was superior in only 4/14 patients (28.6%). For the cerebral cortex, T1- and DWI were similar in lesion conspicuity (5/13 patients and 6/13 patients, respectively). For the white matter, HIE lesions were most conspicuous on DWI in a majority of the study patients. Lesions were detected in the cerebral white matter in 16/20 patients (80.0%), lesions were detected in the PLIC in 11/12 patients (91.7%), lesions were detected in the corticospinal tract in the brain stem in 11/11 patients (100%) and lesions were detected in the cerebellar white matter in one patient (100%).
CONCLUSION
In neonates with HIE, white matter lesions are most conspicuous on DWI, whereas gray matter lesions tend to have greater conspicuity on T1-weighted images than on the other MR sequences.
- Full Text Links
-
- Actions
-
Cited
- CITED
-
- Close
- Share
-
- Similar articles
-
- Clinical Significance of MRI in Hypoxic-Ischemic Encephalopathy During Neonatal Period
- Neurodevelopmental Outcomes According to Brain Injury Patterns in Neonates with Postasphyxial Hypoxic Ischemic Encephalopathy
- Diffusion-weighted MR Imaging of Hypoxic-Ischemic Encephalopathy
- A Comparison of Lesion Detection and Conspicuity on T2-weighted Images (T2 FFE), FLAIR and Diffusion-weighted Images in Patients with Traumatic Brain Injury
- Comparison of Non-Breath-Hold T2-weighted Turbo Spin-Echo and Three Breath-Hold T2-weighted MR Images for Detection of Focal Hepatic Lesion
