J Korean Soc Neonatol.
2008 Nov;15(2):183-189.
A Congenital Giant Hepatic Hemangioendothelioma Treated with Interferon-alpha and Complete Tumor Resection
- Affiliations
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- 1Department of Pediatrics, Ajou University School of Medicine, Suwon, Korea. jeyumd@ajou.ac.kr
- 2Department of Surgery, Ajou University School of Medicine, Suwon, Korea.
- 3Department of Pathology, Ajou University School of Medicine, Suwon, Korea.
Abstract
- Infantile hepatic hemangioendotheliomas (IHHEs) are benign vascular tumors, but can be associated with the life-threatening complications, such as congestive heart failure, disseminated intravascular coagulation, and massive bleeding. Various therapeutic options have been developed and the treatment response depends on the patient's clinical status and the nature of the lesion. In the case of a symptomatic IHHE, a non-invasive and precise diagnosis should be performed promptly before the therapeutic method is chosen. Additionally, it should be kept in mind that the residual lesions have malignant potential. We report a case of a congenital giant IHHE that was successfully reduced in size by interferon-alpha and completely removed by surgical tumor resection with a hepatic lobectomy.
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