Clin Pediatr Hematol Oncol.
2009 Apr;16(1):54-58.
Effective Management of Kaposiform Hemangioendotheliomas Associatedwith Kasabach-Merritt Syndrome Using Chemotherapy
- Affiliations
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- 1Department of Pediatrics, Inha University College of Medicine, Incheon, Korea. pedkim@inha.ac.kr
- 2Department of Dermatology, Inha University College of Medicine, Incheon, Korea.
- 3Department of Pathology, Inha University College of Medicine, Incheon, Korea.
Abstract
- Although Kaposiform hemangioendothelioma (KHE) is a rare benign tumor, it is well known for its aggressiveness, showing mortality rates as high as 24% when progressed to Kasabach- Meritt syndrome. There are various therapies for KHE, such as oral prednisolone, intravenous methylprednisolone, interferon-alpha, surgical resection, chemotherapy and radiotherapy. We report a case of Kasabach-Meritt syndrome, which showed no response to oral prednisolone, intravenous methylprednisolone nor interferon-alpha, but a successful response to chemotherapy.
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