Korean J Nephrol.
2008 Sep;27(5):584-588.
A Case of Immunoglobulin A Nephropathy with Nephrotic Syndrome in a Patient with Behcet's Disease
- Affiliations
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- 1Department of Internal Medicine, Catholic University of Daegu School of Medicine, Daegu, Korea. ihlee@cu.ac.kr
Abstract
- Behcet's disease (BD) is a rare multisystemic vasculitis characterized by recurrent oral and genital ulcers, uveitis, and skin lesions. Renal involvement in BD is more frequent than has been recognized. However, there have been a few reports of glomerulonephritis associated with BD in Korea. We report here a case of IgA nephropathy with nephrotic syndrome in a patient with BD. A 44-year-old woman with BD was admitted for generalized edema which had developed 1 month ago. Routine renal workup revealed heavy proteinuria and gross hematuria. Twenty-four hour urinary protein excretion was 9.8 g/day. Renal biopsy demonstrated IgA nephropathy. She was treated with oral prednisolone, colchicine and azathioprine. The edema and proteinuria gradually improved. Three months later, urine protein to creatinine ratio decreased to 1.8 and her renal function was well preserved.
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