Korean J Med.  2005 Mar;68(3):329-333.

A case of IgA nephropathy in a patient with Behcet's disease

Affiliations
  • 1Department of Internal Medicine, Yonsei University College of Medicine, The Institute of Kidney Disease, Seoul, Korea. khchoi6@yumc.yonsei.ac.kr
  • 2Department of Dermatology, Yonsei University College of Medicine, The Institute of Kidney Disease, Seoul, Korea.
  • 3Department of Pathology, Yonsei University College of Medicine, The Institute of Kidney Disease, Seoul, Korea.

Abstract

Behcet's disease is a multisystem disorder characterized by oral and genital ulcers, uveitis, and skin lesions. Renal involvement has rarely been observed in Behcet's disease. However, pathological reports have revealed various lesions, especially, amyloidosis, focal and segmental glomerulonephritis with crescents, and IgA nephropathy. A 49-year old female with Behcet's disease was admitted to evaluate proteinuria and microscopic hematuria, and renal biopsy showed IgA nephropathy (subclass V). Immunohistology revealed mesangial deposits of IgA and staining for C3. We report a case of IgA nephropathy which was diagnosed by renal biopsy in a patient with Behcet's disease.

Keyword

Behcet's disease; IgA nephropathy

MeSH Terms

Amyloidosis
Biopsy
Female
Glomerulonephritis
Glomerulonephritis, IGA*
Hematuria
Humans
Immunoglobulin A*
Middle Aged
Proteinuria
Skin
Ulcer
Uveitis
Immunoglobulin A
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