Korean J Blood Transfus.  2009 Aug;20(2):134-137.

A Case of Anti-Jk(a) Whose Reactivity Was Abolished in an Enzyme Gel Test

Affiliations
  • 1Department of Laboratory Medicine, Soonchunhyang University Hospital, Seoul, Korea. jwshin@hosp.sch.ac.kr

Abstract

We report a case of Anti-Jk(a), whose reactivity was abolished in an enzyme gel test. A 56-year-old woman was admitted to our hospital because of fever, myalgia, nausea and vomiting. Anti-Jk(a) was detected by antibody screening and an identification test using a LISS/Coombs gel card (DiaMed AG, Cressier sur Morat, Switzwerland). Its reactivity was so weak (trace ~ 1+) that an Enzyme gel card (DiaMed AG) was added to enhance the reactivity. Unexpectedly, all reactions with the enzyme-treated cells showed negative results. The patient's RBC phenotype was Jk(a-b+). The abdominal CT revealed a 6x7.5 cm sized liver abscess. Her condition improved after percutaneous catheter drainage and she was discharged on the 23rd hospital day.

Keyword

Anti-Jk(a); LISS/Coombs gel card; Enzyme gel card

MeSH Terms

Catheters
Drainage
Female
Fever
Humans
Liver Abscess
Mass Screening
Middle Aged
Nausea
Phenotype
Vomiting
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