Clin Exp Otorhinolaryngol.  2009 Dec;2(4):198-202. 10.3342/ceo.2009.2.4.198.

Temporal Bone Myeloid Sarcoma

• Chang KH
• Kim DK
• Jun BC
• Park YS

• KMID: 1466498
• DOI: http://doi.org/10.3342/ceo.2009.2.4.198

Abstract

Myeloid sarcoma is a rare condition that's caused by the aggregation of immature myeloid cells in leukemic patients. Myeloid sarcoma occurring in the temporal bone more frequently involves the mastoid bone than is the case for metastatic lesions arising from non-systemic malignancies. The disease is difficult to diagnose when it presents with symptoms that mimic otomastoiditis. However, an early diagnosis is important in order to achieve complete remission of the disease. Magnetic resonance imaging of the temporal bone is useful for making the diagnosis of myeloid sarcoma, and especially to evaluate the extent of disease. High-dose radio- or chemotherapies are the first-line approaches and possibly the only approaches to achieve complete remission and to cure the disease. With the aim of improving our understanding of myeloid sarcoma in the temporal bone, the present report describes our experience with 5 such cases and we compare the clinical features of these 5 patients with those clinical features of patients who have metastatic lesions.

Keyword

Myeloid sarcoma; Temporal bone

MeSH Terms

Early Diagnosis
Humans
Hydrazines
Magnetic Resonance Imaging
Mastoid
Myeloid Cells
Sarcoma, Myeloid
Temporal Bone
Hydrazines

Figure

• 

  Fig. 1 Radiologic evaluation of myeloid sarcoma (case 1) showing erosion of the mastoid cortex (arrow) and extension of the mass into the external auditory canal.

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  Fig. 2 Relatively homogenously enhanced myeloid sarcoma (case 2) is seen filling the left mastoid (asterisk) and the subcutaneous layer over the mastoid cortex. It is uncertain whether there is a connection between the mastoid and the subcutaneous layer.

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