J Korean Surg Soc.  2009 Apr;76(4):259-261. 10.4174/jkss.2009.76.4.259.

Tetanus in a Breast Cancer Patient with Adjuvant Chemotherapy

Affiliations
  • 1Department of Surgery, St. Mary's Hospital, The Catholic University of Korea College of Medicine, Seoul, Korea. wcpark@catholic.ac.kr

Abstract

Tetanus is a neurologic disorder caused by a tetanoplasmin which is a neurotoxin elaborated by Clostridium tetani. It is characterized by increased muscle tone and spasm. Since a nationwide childhood vaccination program, tetanus has become a rare disease in Korea. Because many physicians have little experience, misdiagnosis or therapeutic delay may result in unexpected consequences. Although it has high mortality rate on attack, early detection, proper immunization and supportive care can increase survival rate. We report a case of tetanus due to puncture injury by splinter in a 69-year-old woman who has been treated with adjuvant chemotherapy of breast cancer. She was admitted to emergency room with difficulty of opening mouth for 3 days. After two days, we detected that the patient suddenly fell on her back with muscle spasm, so we diagnosed her with tetanus. She was given human tetanus immunoglobulin intramuscularly and supportive care. Forty days after admission, she was discharged without complications.

Keyword

Tetanus; Breast cancer; Chemotherapy

MeSH Terms

Aged
Breast
Breast Neoplasms
Chemotherapy, Adjuvant
Clostridium tetani
Diagnostic Errors
Emergencies
Female
Humans
Immunization
Immunoglobulins
Korea
Mouth
Muscles
Nervous System Diseases
Punctures
Rare Diseases
Spasm
Survival Rate
Tetanus
Vaccination
Immunoglobulins

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