Korean J Otorhinolaryngol-Head Neck Surg.  2010 Feb;53(2):121-125. 10.3342/kjorl-hns.2010.53.2.121.

A Case of Tramadol Induced Asthma Attack in a Patient with Samter's Triad

Affiliations
  • 1Department of Otolaryngology -Head and Neck Surgery, Sanggye Paik Hospital, Inje University College of Medicine, Seoul, Korea. entr1@naver.com

Abstract

Samter's triad is a well known syndrome and is characterized by a triad of asthma, aspirin or NSAID sensitivity and chronic sinusitis with nasal polyp. Chronic sinusitis with Samter's triad is difficult to treat completely and has poor prognosis. Tramadol is a non-opioid analgesic that rarely shows respiratory suppression and is known to be relatively safe because it does not inhibit prostaglandin synthesis. For that reason, patients with asthma may avoid drug-induced exacerbations of the disease by substituting Tramadol for NSAIDs. We experienced a case of asthma attack in a patient with Samter's triad after Tramadol injection.

Keyword

Samter's triad; Tramadol; Asthma attack

MeSH Terms

Anti-Inflammatory Agents, Non-Steroidal
Aspirin
Asthma
Humans
Nasal Polyps
Prognosis
Sinusitis
Tramadol
Anti-Inflammatory Agents, Non-Steroidal
Aspirin
Tramadol
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