J Korean Neurol Assoc.
2010 Feb;28(1):56-58.
An Autopsy Case of Multiple System Atrophy
- Affiliations
-
- 1Department of Neurology, National Health Insurance Corporation Ilsan Hospital, Koyang, Korea.
- 2Department of Neurology, Yonsei University College of Medicine, Seoul, Korea. philsland@chol.net
- 3Department of Pathology, Yonsei University College of Medicine, Seoul, Korea.
Abstract
- Multiple-system atrophy (MSA) is an adult-onset, sporadic, progressive neurodegenerative disease. Clinically, the cardinal features include autonomic failure, parkinsonism, cerebellar ataxia, and pyramidal signs in any combination, of which autonomic failure is an integral component in the diagnosis. Pathologically, MSA is characterized by alpha-synuclein-positive glial cytoplasmic inclusions and neuronal loss, predominantly in the basal ganglia, brainstem, cerebellum, and intermediolateral cell columns of the spinal cord. We report the first case of MSA confirmed by autopsy in Korea.
- Full Text Links
-
- Actions
-
Cited
- CITED
-
- Close
- Share
-
- Similar articles
-
- The ‘Hot Cross Bun’ Sign Is Not Always Multiple System Atrophy: Etiologies of 11 Cases
- A Case of Wernicke's Encephalopathy in a Patient with Multiple System Atrophy
- A Patient with Spinocerebellar Ataxia 2 Presenting with Multiple System Atrophy
- Risus Sardonicus in Multiple System Atrophy
- Emerging of Explosive Speech after Olanzapine in Multiple System Atrophy Patient
