Asian Spine J.  2011 Sep;5(3):192-195. 10.4184/asj.2011.5.3.192.

Primary Lumbo-sacral Spinal Epidural Non-Hodgkin's Lymphoma: A Case Report and Review of Literature

• Mally R
• Sharma M
• Khan S
• Velho V

• KMID: 1444936
• DOI: http://doi.org/10.4184/asj.2011.5.3.192

Abstract

We present a case of 24-year-old male presented with low back pain radiating to the left lower limb, tingling numbness and weakness of 6 months duration. Magnetic resonance imaging scan with contrast reveals an extradural mass at lumbosacral region. Patient was operated with laminectomy and complete excision of the lesion was done. Patient's radicular pain relieved following the surgery and weakness also improved. Histopathology was suggestive of non-Hodgkin's lymphoma. Patient received chemotherapy which was followed by radiotherapy. Primary Non-Hodgkin's lymphoma of the lumbosacral spinal epidural tissue is an uncommon lesion. Lymphoma involves the central nervous system in 5-11% of cases either at presentation of the disease or during its course. The spinal epidural tissue is involved primarily in 0.1-3.3% of cases with spinal cord compression being the commonest presentation. Excision of the lesion followed by chemotherapy and radiotherapy is required to achieve cure.

Keyword

Lumbosacral region; Spinal; Epidural; Non-Hodgkin's lymphoma

MeSH Terms

Central Nervous System
Humans
Hypesthesia
Laminectomy
Low Back Pain
Lower Extremity
Lumbosacral Region
Lymphoma
Lymphoma, Non-Hodgkin
Magnetic Resonance Imaging
Male
Spinal Cord Compression
Young Adult