Korean J Pathol.
2011 Oct;45(5):529-531. 10.4132/KoreanJPathol.2011.45.5.529.
Childhood Asymmetry Labium Majus Enlargement
- Affiliations
-
- 1Department of Pathology, Daegu Fatima Hospital, Daegu, Korea. gmjap@fatima.or.kr
- 2Department of Surgery, Daegu Fatima Hospital, Daegu, Korea.
- KMID: 1443705
- DOI: http://doi.org/10.4132/KoreanJPathol.2011.45.5.529
Abstract
- Childhood asymmetry labium majus enlargement (CALME) is a disctinctive clinicopathologic entity of pre- and early puberty first described in 2005. It is defined as an expansion of normal soft tissues of the vulva. Although CALME is not a rare lesion, it has been called lipoma, fibroma, hamartoma, and fibrous hyperplasia. CALME is not a true neoplasm and is a physiologic growth in response to hormone. It may tend to resolve spontaneously and recur after surgical resection. We report four cases of CALME with a review of the literature. To the best of the knowledge, this is the first Korean report.
