J Korean Soc Ultrasound Med.
2012 Jun;31(2):63-72.
Ultrasonography of Neonatal Cholestasis
- Affiliations
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- 1Department of Radiology and Institute of Radiation Medicine of Seoul National University Medical Research Center, Seoul National University College of Medicine, Korea. cheonje@snu.ac.kr
Abstract
- Ultrasonography (US) is as an important tool for differentiation of obstructive and non-obstructive causes of jaundice in infants and children. Beyond two weeks of age, extrahepatic biliary atresia and neonatal hepatitis are the two most common causes of persistent neonatal jaundice; differentiation of extrahepatic biliary atresia, which requires early surgical intervention, is very important. Meticulous analysis should focus on size and configuration of the gallbladder and anatomical changes of the portahepatis. In order to narrow the differential diagnosis, combined approaches using hepatic scintigraphy, MR cholangiography, and, at times, percutaneous liver biopsy are necessary. US is useful for demonstrating choledochal cyst, bile plug syndrome, and spontaneous perforation of the extrahepatic bile duct.
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