J Korean Surg Soc.  2012 Jan;82(1):50-53. 10.4174/jkss.2012.82.1.50.

Post-transplant lymphoproliferative disorder presented as small bowel intussusception in adult liver transplant patient

Affiliations
  • 1Department of Surgery, University of Miami School of Medicine, Miami, FL, USA. JMoon@med.miami.edu
  • 2Department of Surgery, Kyung Hee University School of Medicine, Seoul, Korea.
  • 3Department of Medicine, University of Miami School of Medicine, Miami, FL, USA.
  • 4Department of Pathology, University of Miami School of Medicine, Miami, FL, USA.

Abstract

Intestinal obstruction after liver transplant is a rare complication, with diverse clinical manifestations. Intestinal adhesion is the most common cause. However, internal hernia, abdominal wall hernia, and neoplasm are also reported. Intussusception is another rare cause of intestinal obstruction, which has been reported primarily in pediatric patients. Herein, we report a case of intestinal obstruction from intussusception in an adult liver transplant patient associated with post-transplant lymphoproliferative disorder.

Keyword

Lymphoproliferative disorders; Intussusception; Liver transplantation

MeSH Terms

Adult
Hernia
Hernia, Abdominal
Humans
Intestinal Obstruction
Intussusception
Liver
Liver Transplantation
Lymphoproliferative Disorders
Transplants

Figure

  • Fig. 1 Simple abdominal X-ray presents multiple dilated small bowel loops.

  • Fig. 2 Operative finding shows 4 × 4 cm sized mass which located 300 cm distal from ligament of Treitz and occluded the lumen of the jejunum by formation of intussusception.

  • Fig. 3 (A, B) Low power view of tumor cells infiltrating the mucosal wall and approaching the serosa (H&E, ×40). (C) High power view of the tumor cells displaying prominent centroblastic features (H&E, ×400).

  • Fig. 4 (A, B) CD20 and CD79a, tumor cells displaying B-cell markers by Immunohistochemistry (H&E, ×200). (C, D) CD10 and BCL-6, tumor cells displaying germinal center phenotype by immunohistochemistry (H&E, ×200).


Reference

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