J Korean Soc Spine Surg.  2012 Sep;19(3):97-102. 10.4184/jkss.2012.19.3.97.

The Prognostic Factor of Posterolateral Fusion in Degenerative Spondylolisthesis

Affiliations
  • 1Department of Orthopaedic Surgery, School of Medicine, Inje University, Busan, Korea. staewoo81@naver.com

Abstract

STUDY DESIGN: A retrospective analysis of the posterolateral fusion in degenerative spondylolisthesis.
OBJECTIVES
Posterolateral fusion has been performed for patients about Meyerding grade1, 2 with degenerative spondylolisthesis in L4-5. We evaluated the prognostic factors of posterolateral fusion, alone for degenerative spondylolisthesis. SUMMARY OF LITERATURE REVIEW: It is reported that posterolateral fusion has almost equal postoperative clinical and radiographic results with the interbody or circumferential fusion for spondylolisthesis. However, there have been some unsatisfactory results after posterolateral fusion alone and the causes are yet unknown. MATERIAL AND METHODS: From January 2002 to July 2008, we analyzed postoperative clinical outcomes of 42 patients who were diagnosed with Meyerding 1 or 2 grade degenerative spondylolisthesis at L4-5. All the patients were classified into group I and group II, based on the clinical outcome evaluation method by Kirkaldy-Willis. Ten patients (Group I) were found to have poor or fair clinical outcomes, while 32 patients (Group II) were found to have excellent or good clinical outcomes. The mean duration of the follow up was 16.3 (12-23) months. We looked into postoperative body mass index and bone mass density, and found degenrative lumbar disc through preoperative MRI, retrospectively. We measured angular motion by dynamic radiographs and preoperative slip angle through a Taillard method.
RESULTS
In group I, the average preoperative BMI was 25.7 (21.2~31.4) and the average T score of bone density was -3.0 (-1.9~-4.2). There was 1 case of Grade 3, 3 cases of Grade 4 and 6 cases of Grade 5 by preoperative Pfirmann classification. The average angular motion was 11.8 (9.1~14.2) and the average preoperative slip angle was 8.4 (6.9-9.6). In group II, the average preoperative BMI was 24.3 (20.72~28.1) and the average T score of bone density was -2.1 (-0.9~-3.1). There were 26 cases of Grade 3, 5 cases of Grade 4 and 1 case of Grade 5 by preoperative Pfirmann classification. The average angular motion was 8.8 (6.2~12.1) and the average preoperative slip angle was 6.2 (3.6-7.9). There were statistically significant differences between the two groups in BMI, stage of disc degeneration, preoperative angular motion, and slip angle. (p=0.04, 0.04, 0.05, 0.03, respectively)
CONCLUSION
We concluded that posterolateral fusion has exhibited worse clinical results in cases of BMI less than -2.8, disc degeneration greater than grade 4, angular motion greater than 9.4 degrees, and slip angle greater than 7.1 degrees; as such, we need to consider other surgical methods.

Keyword

Degenerative spondylolisthesis; Posterolateral fusion; Prognostic factor

MeSH Terms

Body Mass Index
Bone Density
Follow-Up Studies
Humans
Intervertebral Disc Degeneration
Retrospective Studies
Spondylolisthesis

Figure

  • Fig. 1. ROC curves


Reference

1.Lionel N. Metz, BS Vedat Deviren. Low-grade spondylo-listhesis. Neurosurg Clin N Am. 2007. 18:237–48.
2.Agazzi S., Reverdin A., May D. Posterior lumbar interbody fusion with cages: an independent review of 71 cases. J Neurosurg. 1999. 91(suppl):186–92.
Article
3.Song KJ., Kim SJ. Surgical treatment for the low grade lumbar isthmic spondylolisthesis: comparison between posterolateral fusion and posterior lumbar interbody fusion. J Kor Soc Spine Surg. 1999. 6:96–103.
4.Herkowitz HN., Kurz ST. Degenerative lumbar spon-dylolisthesis with spinal stenosis. J Bone Joint Surg Am. 1991. 73:802–8.
5.Charles Dean Ray. Threaded titanium cages for lumbar interbody fusions. Spine. 1997. 22:667–79.
6.Gyorgy I., Csecsei ph D., Almos P. Klekner Jozsef Dobal. Posterior interbody fusion using laminectomy bone and transpedicular screw fixation in the treatment of lumbar spondylolisthesis. Spine. 2000. 53:2–7.
7.Zhao Jie., Yong Hai., Nathaniel R. Ordway, Choon Keun. Posterior lumbar interbody fusion using posterolateral placement of a single cylindrical threaded cage. Spine. 2000. 25:425–30.
8.Suk KS., Jeon CH., Lee HM., Kim NH., Kim HC. Compari-son between posterolateral fusion with pedicle screw fixation and anterior interbody fusion with pedicle screw fixation in sondylolisthesis of the lumbar spine. J Kor Soc Spine Surg. 1999. 6:397–406.
9.Ricciard JE., Pflueger PC., Isaza JE., Whitecloud TS 3rd. Transpedicular fixation for the treatment of isthmic spon-dylolisthesis. Spine. 1995. 10:821–27.
10.Shin BJ., Min KD., Kwon H, et al. Surgical results of isthmic spondylolisthesis-Comparison of posterolateral fusion vs. PLIF. J Kor Soc Spine Surg. 1996. 3:61–8.
11.Csecsei G., Klekner AP., Dobai J., Lajgut A., Sikula J. Posterior interbody fusion using laminectomy bone and transpedicular screw fixation in the treatment of lumbar spondylolis-thesis. Surg Neural. 2000. 53:2–6.
12.Christian WA. Pfirmann, Alexander Metzdorf: Magnetic resonance classification of lumbar intervertebral disc degeneration. Spine. 2001. 26:1873–8.
13.Kirkaldy-Willis WH., Panie KWR., Cauchoix J., McIvor G. Lumba spinal stenosis. Clin Orthop. 1974. 99:30–52.
14.Crenshaw AH. Spondylolisthesis. Campbell's operative or-thopedics. 8th ed. 1992. 14:3243–51.
15.Kim YT., Lee CS., Na HY., Lee CW. A comparison of surgical treatment in isthmic and degenerative spondylolisthesis. J Korean Orthop Assoc. 1998. 33:1627–34.
Article
16.Lombardi JS., Wiltes LL., Reynolds J., Widell EH. Treatment of degenerative spondylolisthesis. Spine. 1985. 10:821–27.
Article
17.Dilip K. Sengupta, Hnarry N. Herkowitz. Degenerative spondylolisthesis. 2005. 30(suppl):71–81.
18.Lenke LG., Birdwell KH., Bullis D., Betz RR., Baldus C. Results of in situ fusions for isthmics spondylolisthesis. J Spinal Disorder. 1992. 5:433–41.
19.Kim SS., Denis F., Lonstein JE., Winter RE. Factors affecting fusion rate in adult spondylolisthesis. Spine. 1990. 15:979–84.
Article
20.Halvorson TL., Kelley LA., Thomas KA., Whitecloud TS 3rd., Cook SD. Effects of bone mineral density on pedicle screw fixation. Spine. 1994. 19:2415–20.
Article
21.O'Brien MF. Low-grade isthmic/lytic spondylolisthesis in adults. Inst Course Lect. 2003. 52:511–24.
22.Montgomery DM., Fischgrund JS. Passive reduction of spondylolisthesis on the operating room table: a prospective study. J Spinal Disord. 1994. 7:167–72.
Full Text Links
  • JKSS
Actions
Cited
CITED
export Copy
Close
Share
  • Twitter
  • Facebook
Similar articles
Copyright © 2024 by Korean Association of Medical Journal Editors. All rights reserved.     E-mail: koreamed@kamje.or.kr