J Korean Neurosurg Soc.  2012 Dec;52(6):561-563. 10.3340/jkns.2012.52.6.561.

Desmoplastic Fibroma of the Cranium in a Young Man

Affiliations
  • 1Department of Neurosurgery, College of Medicine, Seoul National University, Seoul, Korea.
  • 2Department of Pathology, The Armed Forces Capital Hospital, Seongnam, Korea.
  • 3Department of Neurosurgery, The Armed Forces Capital Hospital, Seongnam, Korea.
  • 4Department of Neurosurgery, Bucheon St. Mary's Hospital, College of Medicine, The Catholic University of Korea, Bucheon, Korea. armada1997@naver.com

Abstract

Desmoplastic fibroma, which develops predominantly in long bones and the mandible, is a rare and benign but locally aggressive tumor. Desmoplastic fibroma of the cranium is extremely rare. We report a case of desmoplastic fibroma of the frontal bone in a young man. Because of its locally aggressive behavior, complete surgical excision with a safety margin is essential.

Keyword

Desmoplastic fibroma; Frontal bone; Skull

MeSH Terms

Fibroma, Desmoplastic
Frontal Bone
Mandible
Skull

Figure

  • Fig. 1 A : CT scan demonstrating focal calvarial thickening of right frontal skull. B, C and D : MRI reveals intermediate signal intensity on T1-weighted images and heterogeneous intensity on T2-weighted images with multifocal enhancement.

  • Fig. 2 A : Micrograph of the lesion showing spindle cell proliferation with hemorrhage and fat necrosis (H&E, ×100). B : Note fibroblastic proliferation with collagenous background (H&E, ×200). C : Smooth muscle actin staining revealed focal positivity (×200).


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