J Korean Soc Radiol.  2013 Apr;68(4):329-332. 10.3348/jksr.2013.68.4.329.

Radiologic Imaging Findings of Bilateral Infiltrating Pseudoangiomatous Stromal Hyperplasia of the Breasts: A Case Report

• Go HS
• Jeh SK

• KMID: 1425149
• DOI: http://doi.org/10.3348/jksr.2013.68.4.329

Abstract

Pseudoangiomatous stromal hyperplasia (PASH), first described by Vuitch et al., is a rare benign lesion, shows the proliferation of the breast stromal tissue. We experienced a case of a 19-year-old woman with bilateral PASH manifesting as marked enlargement of the breasts for a duration of several months. Morphologic evaluation of imaging modalities was done, including ultrasound, computed tomography and magnetic resonance images. Here, we describe bilateral PASH in a young girl presenting as bilateral breast gigantism from a main point of radiologic image finding.

MeSH Terms

Angiomatosis
Breast
Breast Diseases
Female
Gigantism
Humans
Hyperplasia
Magnetic Resonance Spectroscopy
Angiomatosis
Breast Diseases
Hyperplasia

Figure

• 

  Fig. 1 A 19-year-old female has massive enlargement of both breasts. A. On ultrasound, normal parenchymal structure (*) is mixed with heterogenously hypoechoic and infiltrating lesion. B. Ill-defined cystic structures are scattered with the lesion. C. On non-enhanced CT scan, the lesions on both breasts show relatively homogeneous density with focal fatty nodules. The retromammary fat is preserved well. D, E. These reveal heterogeneously high signal intensity on T2 weighted images (D) and homogeneously low signal intensity on T1 weighted images (E). F. On fat saturated, contrast-enhanced T1 weighted images, heterogeneous enhancement (arrows) is noted. G. The microscopic image (hematoxylin and eosin stained section, × 100) reveals that proliferation of stromal components with diffuse network of spaces in the collagen stroma and vascular channel-like space. H. In immunohistochemistry (× 100), it shows the positive stain of CD34.

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