J Korean Med Sci.
1992 Mar;7(1):79-84. 10.3346/jkms.1992.7.1.79.
POEMS syndrome: a case report
- Affiliations
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- 1Department of Neurology, College of Medicine, Dong-A University, Korea.
- KMID: 1421896
- DOI: http://doi.org/10.3346/jkms.1992.7.1.79
Abstract
- POEMS syndrome is a multisystem disorder associated with polyneuropathy, organomegaly, endocrinopathy, a monoclonal protein (M-protein), and skin changes. The authors describe a patient with POEMS syndrome who had osteosclerotic myeloma confirmed by open bone biopsy. Magnetic resonance imaging (MRI) showed discrete lesions of low signal intensity in both T1 and T2-weighted images. This patient is now being successfully treated with melphalan and prednisone with much improvement in skin thickening and sensory change in the lower extremities.
