Korean J Dermatol.
2004 Jul;42(7):874-879.
Two Cases of POEMS Syndrome Presenting As Glomeruloid Hemangioma
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- 1Department of Dermatology, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea. eslee@smc.samsung.co.kr
Abstract
- Glomeruloid hemangioma is a histologically distinctive cutaneous hemangioma that has recently been associated with POEMS (polyneuropathy, organomegaly, endocrinopathy, monoclonal gammopathy, and skin changes) syndrome. We report two cases of glomeruloid hemangioma associated with POEMS syndrome. Histopathology of two cases showed multiple dilated vascular spaces composed of a conglomerate of capillaries, resulting in structures resembling renal glomeruli. Periodic acid-Schiff positive and diastase-resistant eosinophilic globules were found within the cytoplasm of vacuolated endothelial cells.
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