J Korean Med Sci.  1988 Jun;3(2):63-71. 10.3346/jkms.1988.3.2.63.

Malignant histiocytosis: Clinicopathologic review of 18 cases with immunohistochemical study

• Kim CJ
• Chi JG
• Kim YI

• KMID: 1421287
• DOI: http://doi.org/10.3346/jkms.1988.3.2.63

Abstract

We reviewed clinical and pathologic characteristics of 18 cases of malignant histiocytosis including 2 autopsy cases with special interest on their immunohistochemical characteristics. We report 3 cases of unusual immunohistochemical finding and postulate these cases may be a supportive evidence of the view that dendritic cells share common precursor with those of mononuclear phagocytic system. More accumulated cases in the future and careful analysis would be needed to answer the basic question about the origin of malignant histiocytosis.

Keyword

Malignant histiocytosis; Immunohistochemistry; Histiocytic medullary reticulosis

MeSH Terms

Adolescent
Adult
Antigens, Differentiation/analysis
Biopsy
Child
Dendritic Cells/pathology
Female
Histiocytes/pathology
Histiocytic Sarcoma/immunology/*pathology
Humans
Male
Middle Aged
Tumor Markers, Biological/analysis
Antigens, Differentiation
Tumor Markers, Biological