Korean J Dermatol.
1982 Dec;20(6):945-949.
A Case of Malignant Histiocytosis : Complete Remission with COPP Combination Chemotherapy
Abstract
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Malignant histiocytosis is a rare, usually fatal malignant neoplasm. We present a case of a 62 year-old female with malignant histiocytosis involving the skin, lymph nodes and bone marrow. The patient achieved a complete remission for 1 year after the completion of COPP chemotherapy (cyclophosphamide, vincristine, procarbazine and prednisone). We propose that COPP chemotherapy is a valuable therapeutic regimen for malignant histiocytosis.