J Korean Rheum Assoc.  2008 Mar;15(1):76-80. 10.4078/jkra.2008.15.1.76.

Lobular Panniculitis in a Patient with Dermatomyositis

Affiliations
  • 1Division of Rheumatology, Department of Internal Medicine, The Hospital for Rheumatic Diseases, Hanyang University College of Medicine, Seoul, Korea. junjb@hanyang.ac.kr
  • 2Department of Dermatology, Hanyang University College of Medicine, Seoul, Korea.
  • 3Department of Pathology, Hanyang University College of Medicine, Seoul, Korea.

Abstract

Panniculitis is an inflammation within adipose tissue and most commonly affects the subcutaneous fat. Frequently, the panniculitis is associated with certain drugs and systemic diseases, such as various rheumatologic diseases, idiopathic Weber-Christian disease, infection and malignancy. Panniculitis in dermatomyositis (DM) is most commonly an incidental histopathologic finding that less commonly manifests a clinical component. We report the case of a woman with DM who presented with panniculitis as a clinical finding. A 51-year-old woman was admitted to our hospital with diffuse nodular, indurated, painful erythematous plaques on buttocks, back and chest. 18-months ago, she had been diagnosed DM at our hospital. Her medication on admission was azathioprine. High-dose glucocorticoid was prescribed after the diagnosis of lobular panniculitis confirmed by skin biopsy. After then, the patient was getting better and discharged with the medication tapered.

Keyword

Lobular panniculitis; Dermatomyositis

MeSH Terms

Female
Humans
Biopsy

Figure

  • Fig. 1. Initial skin findings were diffuse nodular, indurated, painful erythematous plaques with multifocal lipoatrophy on buttocks, back (A) and chest (B).

  • Fig. 2. The skin biopsy shows lymphocytes infiltration in the subcutaneous fat lobule (H&E ×400).

  • Fig. 3. After high dose steroid and azathioprine treatment, diffuse erythematous multiple plaques on buttocks, back (A) and chest (B) were decreased.


Cited by  1 articles

Pancreatic Panniculitis in Patients with Chronic Pancreatitis: Case Report and Review of Literature
Eui Joong Kim, Min Su Chu, Ki Chang Sohn, Dong Ho Cho, Ga Hye Na, Haak Cheoul Kim, Eun Young Cho
Korean J Gastroenterol. 2017;69(1):83-86.    doi: 10.4166/kjg.2017.69.1.83.


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