J Korean Rheum Assoc.  2008 Mar;15(1):54-57. 10.4078/jkra.2008.15.1.54.

A Case of Lobular Panniculitis in Dermatomyositis Patient

Affiliations
  • 1Department of Internal Medicine, Catholic University of Deagu School of Medicine, Deagu, Korea. jychoe@cu.ac.kr
  • 2Department of Pathology, Catholic University of Deagu School of Medicine, Deagu, Korea.

Abstract

Panniculitis is an inflammation of subcutaneous fat tissue, and found in variety of clinical setting, like erythema nodosum, lupus or other connective tissue diseases. Panniculitis, as a clinical feature of dermatomyositis, is rare and should be included in one of the sign to be differentiated. We present a 77-year-old female dermatomyositis patient who showed a clinically and histologically evident lobular panniculitis, and successfully treated with oral prednisolone.

Keyword

Dermatomyositis; Panniculitis

MeSH Terms

Female
Humans
Erythema Nodosum

Figure

  • Fig. 1. Photography shows an erythematous and indurated skin rash on right arm.

  • Fig. 2. Ultrasonography of right arm shows a diffuse, increased echogenecity in subcutaneous fat.

  • Fig. 3. Patchy infiltration of lymphocytes in the subcutaneous fat tissue is noted (H&E stain, ×100).


Reference

References

1. Dalakas MC. Polymyositis, dermatomyositis and inclusion-body myositis. N Engl J Med. 1991; 325:1487–98.
Article
2. Janis JF, Winkelmann RK. Histopathology of the skin in dermatomyositis. A histopathologic study of 55 cases. Arch Dermatol. 1968; 97:640–50.
Article
3. Raimer SS, Solomon AR, Daniels JC. Polymyositis presenting with panniculitis. J Am Acad Dermatol. 1985; 13:366–9.
Article
4. Solans R, Cortes J, Selva A, Garcia-Patos V, Jimenez FJ, Pascual C, et al. Panniculitis: a cutaneous manifestation of dermatomyositis. J Am Acad Dermatol. 2002; 46(Supple):148–50.
Article
5. Bohan A, Peter JB. Polymyositis and dermatomyositis (first of two parts). N Engl J Med. 1975; 292:344–7.
6. Kovacs SO, Kovacs SC. Dermatomyositis. J Am Acad Dermatol. 1998; 39:899–920.
Article
7. Callen JP. Dermatomyositis. Lancet. 2000; 355:53–7.
Article
8. Diaz Cascajo C, Borghi S, Weyers W. Panniculitis: definition of terms and diagnostic strategy. Am J Dermatopathol. 2000; 22:530–49.
9. Requena L, Yus ES. Panniculitis. Part I. Mostly septal panniculitis. J Am Acad Dermatol. 2001; 45:163–83.
Article
10. Requena L, Sanchez Yus E. Panniculitis. Part II. Mostly lobular panniculitis. J Am Acad Dermatol. 2001; 45:325–61.
Article
11. Winkelmann RK. Panniculitis in connective tissue disease. Arch Dermatol. 1983; 119:336–44.
Article
12. Neidenbach PJ, Sahn EE, Helton J. Panniculitis in juvenile dermatomyositis. J Am Acad Dermatol. 1995; 33:305–7.
Article
13. Molnar K, Kemeny L, Korom I, Dobozy A. Panniculitis in dermatomyositis: report of two cases. Br J Dermatol. 1998; 139:161–3.
14. Carneiro S, Alvim G, Resende P, Auxiliadora Jeunon Sousa M, Cuzzi T, Ramos-e-Silva M. Dermatomyositis with panniculitis. Skinmed. 2007; 6:46–7.
Article
15. 김재왕, 김진석. 루푸스 지방층염에 대한 임상 및 피 부병리조직학적 고찰. 대한류마티스학회지. 2006; 13:107–15.
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