Yeungnam Univ J Med.
1997 Jun;14(1):94-100. 10.12701/yujm.1997.14.1.94.
The Clinical Study of Clarithromycin for the Treatment of Acute Exacerbation of Chronic Obstructive Pulmonary Disease
- Affiliations
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- 1Department of Internal Medicine College of Medicine, Yeungnam University Taegu, Korea.
- KMID: 1280097
- DOI: http://doi.org/10.12701/yujm.1997.14.1.94
Abstract
- To evaluate the efficacy and safety of clarithromycin in acute exacerbation of chronic obstructive pulmonary disease, we administered clarithromycin(250mg) twice in a day in 30 patients with acute exacerbation of chronic obstructive pulmonary disease from September to November in 1996. Twenty eight eases of 30 patients were cured(93.4%) and 2 cases(6.7%) show clinical improvement. Three cases were improved within 3 days of treatment and 24 cases were improved between 5 days and 12 days of treatment. There were no significant side effects. These results suggest that clarithromycin will be effective as a first line therapy in patients with acute exacerbation of chronic obstructive pulmonary disease.
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