J Korean Rheum Assoc.  2008 Jun;15(2):148-152. 10.4078/jkra.2008.15.2.148.

A Case of Infectious Mononucleosis-like Syndrome Induced by Ceftriaxone and Isepamicin in a Patient with Systemic Lupus Erythematosus

• Do JH
• Ryu SY

• KMID: 1270231
• DOI: http://doi.org/10.4078/jkra.2008.15.2.148

Abstract

A severe adverse reaction to certain drug could be associated with hypersensitivity syndrome, showing the clinical features of infectious mononucleosis including maculopapular rash, fever, lymphadenopathy, leukocytosis, atypical lymphocytes, liver dysfunction, and renal disturbance. We report a systemic lupus erythematosus patient who developed infectious mononucleosis-like syndrome with administration of ceftriaxone/isepamicin for the treatment of pneumonia. This case warrants careful attention to infectious mononucleosis-like syndrome associated with antibiotics administration, especially in febrile patients with known autoimmune diseases such as systemic lupus erythematosus.

Keyword

Infectious mononucleosis-like syndrome; Antibiotics; Ceftriaxone; Isepamicin; Systemic lupus erythematosus

Figure

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  Fig. 1. Chest CT scan shows consolidation with pa-rapneumonic effusion mainly involving left lower lobe with para-pneumonic effusion. (A) Transverse scan and (B) coronal scan.

• 

  Fig. 2. Maculopapular rash of face.

Reference

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