Korean J Med.  2000 Jan;58(1):112-116.

Salmonella osteomyelitis with osteonecrosis in a patient with systemic lupus erythematosus

Affiliations
  • 1Department of Internal Medicine, College of Medicine, The Catholic University of Korea, Seoul, Korea.
  • 2Department of Orthopedics, College of Medicine, The Catholic University of Korea, Seoul, Korea.
  • 3Department of Pathology, College of Medicine, The Catholic University of Korea, Seoul, Korea.
  • 4Department of Radiology, College of Medicine, The Catholic University of Korea, Seoul, Korea.

Abstract

Although infectious diseases are frequent in systemic lupus erythematosus, salmonella osteomyelitis is rarely reported. We here report an unusual case of salmonella osteomyelitis with osteonecrosis in a patient with systemic lupus erythematosus. A 29-year old woman with systemic lupus erythematosus was admitted to our hospital because of a painful swelling of right knee joint. She had been taking steroid and cyclophosphamide for 4 months because of diffuse membranous proliferative lupus nephritis. MRI showed both osteonecrosis of the right distal femur and osteomyelitis of the right proximal tibia. The abscess culture demonstrated almonella species (non typhoidal). The infection was treated successfully by a combination of surgical drainage and intravenous ceftriaxone.

Keyword

Systemic lupus erythematosus; Osteonecrosis; Osteomyelitis; Salmonella infection

MeSH Terms

Abscess
Adult
Ceftriaxone
Communicable Diseases
Cyclophosphamide
Drainage
Female
Femur
Humans
Knee Joint
Lupus Erythematosus, Systemic*
Lupus Nephritis
Magnetic Resonance Imaging
Osteomyelitis*
Osteonecrosis*
Salmonella Infections
Salmonella*
Tibia
Ceftriaxone
Cyclophosphamide
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