J Vet Sci.
2005 Jun;6(2):157-160.
Exploration of immunoblot profiles of Neospora caninum probed with different bovine immunoglobulin classes
- Affiliations
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- 1Institue of Animal Medicine, College of Veterinary Medicine, Gyeongsang National University, Jinju 660-701, Korea. jungts@nongae.gsnu.ac.kr
- 2Department of Molecular Parasitology, School of Medicine, Sungkyunkwan University, Suwon 440-746, Korea.
Abstract
- The present study was attempted to compare the Neospora caninum (N. caninum) antigenic bands recognized by different bovine immunoglobulin classes. A total 10, 5, 2, and 6 antigenic bands were exhibited on immunoblot profiles against bovine IgM, IgE, IgA, and IgG, respectively. A 46 kDa band was probed as a common antigenic band except IgA; 69 kDa band was bovine IgM and IgE; 33, 37, 55, and 79 kDa bands were bovine IgM and IgG; 72 kDa band was found IgM and IgA profiles. Based on the analysis, it appeared that different immunoglobulin classes recognizing different antigenic molecules were cooperating to cope with neosporosis.
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