Korean J Radiol.  2003 Dec;4(4):255-259. 10.3348/kjr.2003.4.4.255.

Carcinosarcoma of the Renal Pelvis and Urinary Bladder: A Case Report

Affiliations
  • 1Department of Radiology, Dokuz Eylul University School of Medicine, 35340, Izmir, Turkey. eyilmaz@deu.edu.tr
  • 2Department of Pathology, Dokuz Eylul University School of Medicine, 35340, Izmir, Turkey.
  • 3Department of Radiation Oncology, Dokuz Eylul University School of Medicine, 35340, Izmir, Turkey.
  • 4Department of Urology, Sisli Etfal Hospital, 80290, I stanbul, Turkey.

Abstract

Carcinosarcomas are rare biphasic malignant neoplasms with an epithelial and a spindle cell component. We present a 62-year-old man with a history of noticeably abdominal distension, proved by surgery to be caused by carcinosarcoma of the renal pelvis and urinary bladder, occupying the entire left abdominal flank. We also illustrate the appearance of this rare entity on sonography and computed tomography.

Keyword

Carcinosarcoma; Computed Tomography (CT) ; Ultrasound; Urothelial system

MeSH Terms

Bladder/*pathology/radiography/surgery/ultrasonography
Bladder Neoplasms/radiography/*surgery/ultrasonography
Carcinosarcoma/radiography/*surgery/ultrasonography
Contrast Media/administration & dosage
Human
Kidney Neoplasms/radiography/*surgery/ultrasonography
Kidney Pelvis/*pathology/radiography/surgery/ultrasonography
Male
Middle Aged
Tomography, X-Ray Computed

Figure

  • Fig. 1 A. Sonogram of 12 cm-mass component located on top of the tumor shows variable echogenity with heterogeneous hyperechoic areas mixed with less echoic areas or small cysts presenting cystic necrosis (arrowheads). B. Transverse sonogram of urinary bladder reveals a small tumor (arrow) arising from the left postero-lateral bladder wall. C-E. Sequential enhanced CT scans through pancreas (C), at the level of the lower abdominal region (D) and the bladder (E). C. Relatively well-defined, heterogeneous tumor seems to originate from the left kidney without any normal tissue apparently preserved from invasion. Obliteration of the fat plane (arrowhead) is seen between the upper-medial portion of the tumor (arrow) and the pancreatic tail corresponding to invasion that was pathologically proven. D. Giant tumor extends caudally as a smoothly marginated mass with considerable displacement of the aorta and the inferior vena cava (arrowhead) at the midline. The tumor displays peripheral and nodular enhancement (arrows), which delineates large, hypodense zone of necrosis. The center has an attenuation value of between 20-25 HU. E. A soft tissue sessile mass (arrow) extends into the bladder lumen. The perivesical fat planes are intact. F. Photograph of resected kidney demonstrates that the tumor involves the entire renal parenchyma and pelvocaliceal system. G. Photomicrograph of histological specimen obtained from renal neoplasm shows nest of transitional cell carcinoma (arrow) in a sarcomatous stroma (H and E, ×100).


Reference

1. Baschinsky DY, Chen JH, Vadmal MS, et al. Carcinosarcoma of the urinary bladder- an aggressive tumor with diverse histogenesis. Arch Pathol Lab Med. 2000. 124:1172–1178.
2. Orsatti G, Corgan FJ, Goldberg SA. Carcinosarcoma of urothelial organs: sequential involvement of urinary bladder, ureter, and renal pelvis. Urology. 1993. 41:289–291.
3. Sumi Y, Shindoh N, Kimizuka T, Katayama H. Carcinosarcoma of the urinary bladder. AJR Am J Roentgenol. 1999. 172:767–769.
4. Meyer R. Beitrag zur Vestandigung uber die Namengebung in der Geschwulstlehre. Zentralbl Allg Path. 1920. 30:291.
5. Willis RA. Carcinoma. Pathology of tumors. 1967. 4th ed. New York: Appleton-Century-Crofts;138.
6. Catalona WJ. Walsh PC, Retik AB, Stamey TA, Vaughan ED, editors. Urothelial tumors of the urinary tract. Campbell's urology. 1992. 6th ed. Philadelphia: WB Saunders;1134–1135.
7. Tekes A, Kamel IR, Szarf G, et al. Carcinosarcoma of the urinary bladder: dynamic contrast-enhanced MR imaging with clinical and pathologic correlation. AJR Am J Roentgenol. 2003. 181:139–142.
8. Kakoi N, Miyajima A, Motizuku T. Carcinosarcoma of the renal pelvis and ureter: a case report. Hinyokika Kiyo. 2002. 48:29–32.
9. Leder RA, Dunnick NR. Transitional cell carcinoma of the pelvicalices and ureter. AJR Am J Roentgenol. 1990. 155:713–722.
10. Shirkhoda A, Lewis E. Renal sarcoma and sarcomatoid renal cell carcinoma: CT and angiographic features. Radiology. 1987. 162:353–357.
Full Text Links
  • KJR
Actions
Cited
CITED
export Copy
Close
Share
  • Twitter
  • Facebook
Similar articles
Copyright © 2024 by Korean Association of Medical Journal Editors. All rights reserved.     E-mail: koreamed@kamje.or.kr