Chonnam Med J.  2010 Aug;46(2):121-124. 10.4068/cmj.2010.46.2.121.

Sarcomatoid Carcinoma in the Urinary Bladder

• Yoo DH
• Jang WH
• Yim JY
• Seo MY
• Park SW

• KMID: 1730010
• DOI: http://doi.org/10.4068/cmj.2010.46.2.121

Abstract

Sarcomatoid carcinoma of the urinary bladder is a rare malignant neoplasm in which the tumor consists of both carcinomatous and sarcomatous elements. In Korea, only 1 case of bladder and renal pelvis primary sarcomatoid carcinoma and 4 cases of carcinosarcoma involving the bladder have been reported. Recently, we experienced a case of sarcomatoid carcinoma of the bladder in a 78-year-old male patient experiencing severe gross hematuria. An ultrasound demonstrated a broad-based tumor 4.5x3.6 cm in size on the lateral side of the right ureteral orifice in the bladder dome. Under the diagnosis of a bladder tumor, transurethral resection of the bladder tumor (TURBT) was performed. A subsequent histological examination of the biopsy specimens showed both malignant mesenchymal and epithelial elements. As a result, the tumor was pathologically confirmed as a primary sarcomatoid carcinoma of the urinary bladder.

Keyword

Urinary bladder; Carcinoma; Carcinosarcoma

MeSH Terms

Aged
Biopsy
Carcinosarcoma
Hematuria
Humans
Kidney Pelvis
Korea
Male
Ureter
Urinary Bladder
Urinary Bladder Neoplasms

Figure

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  Fig. 1 Microscopic findings showing a mixture of carcinomatous and sarcomatous elements. The tumor contains spindle-shaped cells (H&E, ×400).

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  Fig. 2 Immunohistochemical staining for (A) cytokeratin and (B) vimentin (×200). The images reveal the diffuse cytoplasmic positivity in the tumor cells of the sarcomatoid area.

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  Fig. 3 After transurethral resection of the bladder tumor (TURBT), the CT scan shows the irregular thickening of the right lateral wall and perivesical haziness.

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