J Korean Med Sci.  2003 Feb;18(1):48-52. 10.3346/jkms.2003.18.1.48.

The Validity of the ISAAC Written Questionnaire and the ISAAC Video Questionnaire (AVQ 3.0)for Predicting Asthma Associated with Bronchial Hyperreactivity in a Group of 13-14 Year Old Korean Schoolchildren

Affiliations
  • 1Department of Pediatrics, College of Medicine, University of Ulsan, Seoul, Korea. silee@smc.samsung.co.kr
  • 2Department of Pediatrics, College of Medicine, University of Ulsan, Korea.
  • 3Department of Pediatrics, Hanyang University, Korea.
  • 4Department of Pediatrics, Kyunghee University, Korea.
  • 5Department of Pediatrics, Kangnam General Hospital Public Corporation, Korea.
  • 6Department of Pediatrics, Yonsei University, Korea.
  • 7Department of Pediatrics, Seoul National University, Korea.
  • 8Department of Pediatrics, Sungkyunkwan University, Korea.
  • 9Department of Statistics, Samsung Medical Center, Seoul, Korea.

Abstract

To validate the prevalence rate of symptoms of asthma produced by the phase I ISAAC (International Study of Asthma and Allergies in Childhood) study, hypertonic saline challenge test was carried out during the phase II study at a year after the phase I study. For the phase II study, six middle schools from three cities in the phase I study were selected. Finally, 499 children who responded to both studies were analyzed. All subjects were asked to complete the written questionnaire (WQ) first, followed by a video questionnaire (AVQ 3.0) during the phase I study. Of the 499 children, only 19 (3.8%) were positive to the hypertonic saline bronchial challenge test. The degree of agreement between responses to the two corresponding questions "wheezing at rest" and "nocturnal wheeze" in the AVQ 3.0 and WQ were moderate and weak with a Kappa indices of 0.45 and 0.23, respectively. The question on "severe wheeze" in the AVQ 3.0 had the highest Youden's index among the five questions related to asthma symptoms in the previous 12 months, but its specificity was low whereas it 's sensitivity was 1.0. There was no consistency of priority between the two questionnaires in predicting bronchial hyperreactivity in a group of Korean schoolchildren. Therefore we need to develop more appropriate WQ or AVQ to compare the prevalences of asthma to other countries.

Keyword

Asthma; Prevalence; Bronchial Hyperrereactivity; Questionnaires; Written and Video; Child

MeSH Terms

Adolescent
Asthma/diagnosis*
Asthma/epidemiology
Asthma/etiology
Bronchial Hyperreactivity/complications
Bronchial Hyperreactivity/diagnosis*
Bronchial Hyperreactivity/epidemiology
Bronchial Provocation Tests
Comparative Study
Female
Human
Korea/epidemiology
Language
Male
Prevalence
Questionnaires*
Random Allocation
Respiratory Sounds
Saline Solution, Hypertonic/diagnostic use
Sampling Studies
Videotape Recording
Writing

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