Yonsei Med J.  1991 Dec;32(4):362-369. 10.3349/ymj.1991.32.4.362.

Coexisting mycosis fungoides and Hodgkin's disease as a composite lymphoma: a case report

Affiliations
  • 1Dapartment of Internal Medicine, Yonsei University College of Medicine, Seoul, Korea.
  • 2Dapartment of Dermatology, Yonsei University College of Medicine, Seoul, Korea.
  • 3Dapartment of Pathology, Yonsei University College of Medicine, Seoul, Korea.

Abstract

Within the past few years, an increasing number of reports of Hodgkin's disease following the diagnosis of, and frequently coexisting with, mycosis fungoides have appeared. Previously, Hodgkin's disease found in the lymph nodes of the patient diagnosed as mycosis fungoides was considered as a transformed form of the mycosis fungoides. But, now it has been proven that Hodgkin's disease and mycosis fungoides are histologically and immunohistochemically distinct disease entities. We report a well-documented case of a man who developed Hodgkin's disease and mycosis fungoides simultaneously as a composite lymphoma. Our case emphasizes the importance of considering the diagnosis of another lymphoma in patients with mycosis fungoides who have lymphadenopathy. The cutaneous mycosis fungoides and the Hodgkin's disease should be treated as an independent disease.

Keyword

Mycosis fungoides; Hodgkin's disease; composite lymphoma

MeSH Terms

Adult
Case Report
Hodgkin Disease/*pathology
Human
Male
Mycosis Fungoides/*pathology
Neoplasms, Multiple Primary/*pathology
Skin Neoplasms/*pathology
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