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Interruption of Helicobacter pylori-Induced NLRP3 Inflammasome Activation by Chalcone Derivatives

Choi HR, Lim H, Lee JH, Park H, Kim HP

Helicobacter pylori causes chronic gastritis through cag pathogenicity island (cagPAI), vacuolating cytotoxin A (VacA), lipopolysaccharides (LPS), and flagellin as pathogen-related molecular patterns (PAMPs), which, in combination with the pattern recognition...
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Suppressive Impact of Ginsenoside-Rg2 on Catecholamine Secretion from the Rat Adrenal Medulla

Ha KS, Kim KH, Lim HJ, Ki YJ, Koh YY, Lim DY

This study was designed to characterize the effect of ginsenoside-Rg2 (Rg2), one of panaxatriol saponins isolated from Korean ginseng root, on the release of catecholamines (CA) in the perfused model...
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Rapid Onset of Intranasal Esketamine in Patients with Treatment Resistant Depression and Major Depression with Suicide Ideation: A Meta-Analysis

Wang SM, Kim NY, Na HR, Lim HK, Woo YS, Pae CU, Bahk WM

Objective: We performed a meta-analysis of randomized double-blinded placebo controlled trials (DB-RCTs) to investigate efficacy and safety of intranasal esketamine in treating major depressive disorder (MDD) including treatment resistant depression...
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Prediction of Locomotor Activity by Infrared Motion Detector on Sleep-wake State in Mice

Park J, Jung MS, Moon E, Lim HJ, Oh CE, Lee JH

Objective: Behavioral assessments that effectively predict sleep-wake states were tried in animal research. This study aimed to examine the prediction power of an infrared locomotion detector on the sleep-wake states...
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Pre-transplant Dementia is Associated with Poor Survival After Hematopoietic Stem Cell Transplantation: A Nationwide Cohort Study with Propensity Score Matched Control

Wang SM, Park SS, Park SH, Kim NY, Kang DW, Na HR, Bae YY, Lee JW, Han S, Lim HK

Objective: No previous study examined impact of dementia in the outcome of allogeneic hematopoietic stem cell transplantation (HSCT). We aimed to investigate overall survival (OS) of patients with dementia after...
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A Case Report of Cholangiocarcinoma Arising from a Biliary Adenofibroma: Radiologic Findings and Review of Literature

Lim HJ, Park MS, Park YN, Kim SI, Kim YE, Hwang CH

Biliary adenofibromas are rare biliary epithelial tumors that are classified as benign. Nevertheless, some cases have been reported to show malignant transformations. The radiologic findings of biliary adenofibromas and their...
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Factors Affecting Turnover Intention of Nurses Working in Neonatal Intensive Care Units

Jun SH, Lee MH, Shim MS, Lim HN

Purpose: This study was conducted to assess the factors affecting turnover intention of the nurses working in neonatal intensive care units, including the extent of fatigue, work stresses, and work...
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Lifestyle, Health Status and Socioeconomic Factors Associated with Depressive Symptoms in Korean Young Adults: Korean National Health and Nutrition Examination Survey 2017

Chung YJ, Jung HH, Jung C, Lim HS, Kim SC

Background: In recent years, the number of suicides in young adults has increased rapidly, leading to a major social problem. According to several reports, suicide is closely related to depressive...
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Alpha-lipoic acid protects human dopaminergic neuronal cells against hydrogen peroxide-induced cell injury by inhibiting autophagy and apoptosis

Kang KR, Kim JS, Kim TH, Seo JY, Lim H, Park JH, Yang KY, Yu SK, Kim HJ, Kim CS, Chun HS, Lee DS, Park JC, Kim DK

Alpha-lipoic acid (ALA) is a naturally occurring antioxidant and has been previously used to treat diabetes and cardiovascular disease. However, the autophagy effects of ALA against oxidative stress-induced dopaminergic neuronal...
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Pavlov’s Ratio of the Cervical Spine in a Korean Population: A Comparative Study by Age in Patients with Minor Trauma without Neurologic Symptoms

Moon MS, Choi WR, Lim HG, Lee SY, Wi SM

Background: There are many studies on the vertebral body-to-canal ratio, the so-called Pavlov’s ratio of the cervical spine. However, there are no studies on its relation with age to clarify...
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Effects of Wearable Powered Exoskeletal Training on Functional Mobility, Physiological Health and Quality of Life in Non-ambulatory Spinal Cord Injury Patients

Kim HS, Park JH, Lee HS, Lee JY, Jung JW, Park SB, Hyun DJ, Park S, Yoon J, Lim H, Choi YY, Kim MJ

Background: Spinal cord injury (SCI) is a serious clinical condition that impacts a patient's physical, psychological, and socio-economic status. The aim of this pilot study was to evaluate the effects...
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Evidence-Based Guidelines for the Treatment of Helicobacter pylori Infection in Korea 2020

Jung HK, Kang SJ, Lee YC, Yang HJ, Park SY, Shin CM, Kim SE, Lim HC, Kim JH, Nam SY, Shin WG, Park JM, Choi IJ, Kim JG, Choi M, Korean College of Helicobacter and Upper Gastrointestinal Research

Helicobacter pylori infection is one of the most common infectious diseases worldwide. Although the prevalence of H. pylori is gradually decreasing, approximately half of the world's population still becomes infected...
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Treatment Outcomes of Patients with Head and Neck Squamous Cell Carcinoma of Unknown Primary

Park KS, Lim HR, Jeong SH, Lee DH, Lim SC

The purpose of this study was to evaluate clinical characteristics and treatment outcome of patients with head and neck squamous cell carcinoma of unknown primary (HNSCCUP), treated according to the...
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Pictorial Review of Mediastinal Masses with an Emphasis on Magnetic Resonance Imaging

Park JW, Jeong WG, Lee JE, Lee Hj, Ki SY, Lee BC, Kim HO, Kim SK, Heo SH, Lim HS, Shin SS, Yoon W, Jeong YY, Kim YH

Magnetic resonance imaging (MRI) has become a crucial tool for evaluating mediastinal masses considering that several lesions that appear indeterminate on computed tomography and radiography can be differentiated on MRI....
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Effects of implant alignment and load direction on mandibular bone and implant: finite element analysis

Chung H, Park C, Yun KD, Lim HP, Park SW, Yang H

Purpose: To evaluate the effects of load direction, number of implants, and alignment of implant position on stress distribution in implant, prosthesis, and bone tissue. Materials and Methods: Four 3D...
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Symmetry of Optical Coherence Tomography Angiography Parameters between Dominant and Non-dominant Eyes in Healthy Koreans

Kim KM, Lim HB, Shin YI, Jo YJ, Kim JY

Purpose: To assess the symmetry of microvascular parameters measured via optical coherence tomography angiography (OCTA) between the dominant and non-dominant eyes of normal Korean subjects. Methods: We retrospectively analyzed data on...
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Anger-Related Characteristics According to Chronotypes in Bipolar or Depressive Disorders

Kang TU, Moon E, Choi Y, Suh H, Park JM, Lee BD, Lee YM, Jeong HJ, Kim SY, Lee K, Lim HJ, Yoon M

Objective Though anger was highly associated with eveningness in general population, there is no study on the relationship between chronotype and anger-related characteristics in bipolar or depressive disorders. This study...
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Effect of Perfluorobutane Microbubbles onRadiofrequency Ablation for Hepatocellular Carcinoma:Suppression of Steam Popping and Its ClinicalImplication

Jeong DY, Kang TW, Min JH, Song KD, Lee MW, Rhim H, Lim HK, Sinn DH, Han H

Objective: To evaluate the effect of perfluorobutane microbubbles (Sonazoid®, GE Healthcare) on steam popping duringradiofrequency (RF) ablation for treating hepatocellular carcinoma (HCC), and to assess whether popping affects treatmentoutcomes. Materials and...
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Delayed diagnosis of gestational diabetes mellitus and perinatal outcomes in women with large for gestational age fetuses during the third trimester

Sohn J, Lim HJ, Kim S, Kim TH, Kim BJ, Hwang KR, Lee TS, Jeon HW, Kim SM

Objective We evaluated the incidence of newly diagnosed gestational diabetes mellitus (GDM) during the 3rd trimester in women with suspected large for gestational age (LGA) fetuses on ultrasound and assessed...
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Agomelatine for the Treatment of Generalized Anxiety Disorder: A Meta-Analysis

Wang SM, Woo YS, Kim NY, Na HR, Lim HK, Bahk WM

Objective: Despite multiple drugs available, a large proportion of patients with generalized anxiety disorder (GAD) do not show adequate response and remission. Thus, additional novel pharmacological agents are needed to...
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